Registration Dossier
Registration Dossier
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EC number: 203-483-8 | CAS number: 107-35-7
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- (Q)SAR
- Adequacy of study:
- weight of evidence
- Study period:
- 2018
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification
- Justification for type of information:
- QMRF for this informatic tool is not available. However, this informatic tool is widely used and reported in ECHA Practical Guide - How to use and report (Q)SARs, Version 3.1 (July 2016).
1. SOFTWARE : EPI BIOWIN
2. MODEL (incl. version number) : EPI BIOWIN v4.10
The EPI (Estimation Programs Interface) Suite™ is a Windows®-based suite of physical/chemical property and environmental fate estimation programs developed by EPA’s and Syracuse Research Corp. (SRC).
EPI Suite™ uses a single input to run the following estimation programs: KOWWIN™, AOPWIN™, HENRYWIN™, MPBPWIN™, BIOWIN™, BioHCwin, KOCWIN™, WSKOWWIN™, WATERNT™, BCFBAF™, HYDROWIN™, KOAWIN and AEROWIN™, and the fate models WVOLWIN™, STPWIN™ and LEV3EPI™. ECOSAR™, which estimates ecotoxicity, is also included in EPI Suite™.
Data source
Reference
- Reference Type:
- other: QSAR
- Title:
- EPI BIOWIN v4.10
- Author:
- US EPA
- Year:
- 2 018
- Bibliographic source:
- United States Environmental Protection Agency, Washington, DC, USA.
Materials and methods
- Principles of method if other than guideline:
- - Software tool(s) used including version: EPI BIOWIN v4.10
- Model description: see field 'Justification for type of information'
- Justification of QSAR prediction: see field 'Justification for type of information'
The EPI (Estimation Programs Interface) Suite™ is a Windows®-based suite of physical/chemical property and environmental fate estimation programs developed by EPA’s and Syracuse Research Corp.(SRC).
EPI Suite™ uses a single input to run the following estimation programs: KOWWIN™, AOPWIN™, HENRYWIN™, MPBPWIN™, BIOWIN™, BioHCwin, KOCWIN™, WSKOWWIN™, WATERNT™, BCFBAF™, HYDROWIN™, KOAWIN and AEROWIN™, and the fate models WVOLWIN™, STPWIN™ and LEV3EPI™. ECOSAR™, which estimates ecotoxicity, is also included in EPI Suite™.
Test material
- Reference substance name:
- Taurine
- EC Number:
- 203-483-8
- EC Name:
- Taurine
- Cas Number:
- 107-35-7
- Molecular formula:
- C2H7NO3S
- IUPAC Name:
- 2-aminoethanesulfonic acid
- Test material form:
- solid: particulate/powder
Constituent 1
Results and discussion
% Degradation
- Remarks on result:
- not measured/tested
Any other information on results incl. tables
Biodegradability |
Biowin1 (Linear Model Prediction) : Biodegrades Fast Biowin2 (Non-Linear Model Prediction): Biodegrades Fast Biowin3 (Ultimate Biodegradation Timeframe): Weeks Biowin4 (Primary Biodegradation Timeframe): Days Biowin5 (MITI Linear Model Prediction) : Not Readily Degradable Biowin6 (MITI Non-Linear Model Prediction): Not Readily Degradable Biowin7 (Anaerobic Model Prediction): Biodegrades Fast Ready Biodegradability Prediction: NO |
Not Readily Degradable |
*Chemical may not be soluble enough to measure this predicted effect. If the effect level exceeds the water solubility by 10X, typically no effects at saturation (NES) are reported.
Class Specific LogKow Cut-Offs
------------------------------
If the log Kow of the chemical is greater than the endpoint specific cut-offs
presented below, then no effects at saturation are expected for those endpoints.
Aliphatic Amines:
----------------
Maximum LogKow: 6.0 (Fish, Mysid LC50)
Maximum LogKow: 5.0 (Daphnid LC50)
Maximum LogKow: 7.0 (Green Algae EC50)
Maximum LogKow: 8.0 (Fish, Daphnid ChV)
Maximum LogKow: 7.0 (Green Algae ChV)
Baseline Toxicity SAR Limitations:
---------------------------------
Maximum LogKow: 5.0 (Fish 96-hr LC50; Daphnid LC50)
Maximum LogKow: 6.4 (Green Algae EC50)
Maximum LogKow: 8.0 (ChV)
Applicant's summary and conclusion
- Validity criteria fulfilled:
- not applicable
- Interpretation of results:
- not readily biodegradable
- Conclusions:
- Taurine is not readily biodegradable.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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