Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 260-086-2 | CAS number: 56271-94-4
Partition coefficient
Administrative data
Link to relevant study record(s)
- Endpoint:
- partition coefficient
- Type of information:
- (Q)SAR
- Adequacy of study:
- key study
- Study period:
- 19 December 2017
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Justification for type of information:
- Due to the low solubility of the test material in water and octanol, formal testing was not possible. The sponsor has therefore provided the estimation of log Pow being equal -1.01. This is the ChemAxon ‘Consenus’ method which uses a consensus model built on the ChemAxon, Klopman et al. models and the PhysProp database.
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.8 (Partition Coefficient - Shake Flask Method)
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- flask method
- Partition coefficient type:
- octanol-water
- Specific details on test material used for the study:
- SOURCE OF TEST MATERIAL
- Source and lot/batch No.of test material: Sponsor and G316533
- Expiration date of the lot/batch: 25 March 2018
- Purity test date: 22 August 2017 - Key result
- Type:
- log Pow
- Partition coefficient:
- -1.01
- Remarks on result:
- other: estimated value
- Details on results:
- Due to the low solubility of the test material in water and octanol, formal testing was not possible. The sponsor has therefore provided the estimation of log Pow being equal -1.01. This is the ChemAxon ‘Consenus’ method which uses a consensus model built on the ChemAxon, Klopman et al. models and the PhysProp database.
- Conclusions:
- Due to the low solubility of the test material in water and octanol, formal testing was not possible. The sponsor has therefore provided the estimation of log Pow being equal -1.01. This is the ChemAxon ‘Consenus’ method which uses a consensus model built on the ChemAxon, Klopman et al. models and the PhysProp database.
Reference
Description of key information
Due to the low solubility of the test material in water and octanol, formal testing was not possible. The sponsor has therefore provided the estimation of log Pow being equal -1.01. This is the ChemAxon ‘Consenus’ method which uses a consensus model built on the ChemAxon, Klopman et al. models and the PhysProp database.
Key value for chemical safety assessment
- Log Kow (Log Pow):
- -1.01
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
