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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Eye irritation

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Administrative data

Endpoint:
eye irritation: in vivo
Type of information:
experimental study
Adequacy of study:
key study
Study period:
1979
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
guideline study with acceptable restrictions

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1979
Report date:
1979

Materials and methods

Test guideline
Qualifier:
no guideline available
Principles of method if other than guideline:
orientation test
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
Ethylamine-boron trifluoride
EC Number:
200-852-5
EC Name:
Ethylamine-boron trifluoride
Cas Number:
75-23-0
Molecular formula:
C2H7BF3N
IUPAC Name:
ethanamine; trifluoroborane
Specific details on test material used for the study:
not specified

Test animals / tissue source

Species:
rabbit
Strain:
not specified

Test system

Vehicle:
not specified
Amount / concentration applied:
not specified
Duration of treatment / exposure:
not specified
Observation period (in vivo):
not specified
Duration of post- treatment incubation (in vitro):
not specified
Number of animals or in vitro replicates:
not specified
Details on study design:
not specified

Results and discussion

In vivo

Results
Irritation parameter:
other: not specified
Basis:
other: not specified
Time point:
other: not specified
Score:
>= 1.4
Max. score:
1.4
Reversibility:
not specified

Applicant's summary and conclusion

Interpretation of results:
Category 2 (irritating to eyes) based on GHS criteria
Conclusions:
the test report concludes only minimal eye irritation. However, since no detailed description of the observations is available ethylamine-boron trifluoride is precautionary classified as eye irritant