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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Skin irritation / corrosion

Currently viewing:

Administrative data

Endpoint:
skin irritation: in vivo
Type of information:
experimental study
Adequacy of study:
key study
Study period:
1979
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
comparable to guideline study with acceptable restrictions

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1979
Report date:
1979

Materials and methods

Test guideline
Qualifier:
no guideline available
Principles of method if other than guideline:
orientation test
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
Ethylamine-boron trifluoride
EC Number:
200-852-5
EC Name:
Ethylamine-boron trifluoride
Cas Number:
75-23-0
Molecular formula:
C2H7BF3N
IUPAC Name:
ethanamine; trifluoroborane

Test animals

Species:
rabbit
Strain:
not specified

Test system

Type of coverage:
not specified
Preparation of test site:
not specified
Vehicle:
not specified
Controls:
not specified
Amount / concentration applied:
not specified
Duration of treatment / exposure:
not specified
Observation period:
not specified
Number of animals:
not specified
Details on study design:
not specified

Results and discussion

In vivo

Results
Irritation parameter:
other: not specified
Basis:
other: not specified
Time point:
other: not specified
Score:
>= 1.75
Max. score:
1.75
Reversibility:
not specified
Remarks on result:
probability of weak irritation

Applicant's summary and conclusion

Interpretation of results:
Category 2 (irritant) based on GHS criteria
Conclusions:
the test report concludes only slight skin irritation. However, since no detailed description of the observations is available ethylamine-boron trifluoride is precautionary classified as skin irritant irritant