N,N-dimethyl-N-tetradecyltetradecan-1-aminium chloride

Boiling point

Link to relevant study record(s)

Reference

Endpoint:

boiling point

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 103 (Boiling Point)

Version / remarks:

1955

Deviations:

no

Qualifier:

according to guideline

Guideline:

EU Method A.2 (Boiling Temperature)

Version / remarks:

2008

Deviations:

no

GLP compliance:

no

Type of method:

differential scanning calorimetry

Remarks:

+ thermogravimetry

Decomposition:

yes

Decomp. temp.:

>= 179 °C

In the TGA test, a sample of the test item was heated from 30 °C to 455 °C in an inert gas atmosphere (N2). Between 30 °C and 85 °C it lost 0.6 % of its weight, which can be mainly attributed to the partial evaporation of residual iso-propanol and water.

Above 179 °C (onset) the weight continuously decreased and reached a loss of approx. 99.5 % at 360 °C.

Even in the preliminary DSC test an endothermic signal was recorded above 179 °C (178.9 °C (onset) and 231.8 °C (endset)). Thus, with the recorded weight loss this effect could be allocated to a boiling behaviour, however, from the knowledge of the chemical structures this endotherm is most likely allocated to a degradation process.

This assumption can also be deduced from the literature, as it is well known that quaternary structures tend to degrade above temperatures of 120 °C (Hoffmann degradation; reversed Menshutkin reaction). In order to provide evidence for this assumption, a degradation test was performed during which 18.9974 mg of the sample were heated to 230°C for 5 minutes (upper range of the suspected boiling range) and the remaining residue war characterised by NMR spectroscopy. A weight loss of 28.9 % was recorded and according to the NMR analysis, the residue consisted almost exclusively of alkenes, the anticipated degradation product of the Hoffmann degradation. Consequently, the test item does not provide a boiling point but starts to disintegrate at about 179°C.

Conclusions:

No boiling point could be detected; decomposition above 179 °C.

Executive summary:

The boiling point of Di-C12-18 alkyldimethyl ammonium chloride was determined according to OECD Guideline 103 (1995) and EU method A.2 (2008) using thermogravimetry and differential scanning calorimetry. No boiling point was detected; the test item started to disintegrate above 179 °C.

Description of key information

no boiling point, decomposition >179°C (OECD TG 103/EU method A.2; RL1, non-GLP)

Additional information

The boiling point of Di-C12-18 alkyldimethyl ammonium chloride was determined according to OECD Guideline 103 (1995) and EU method A.2 (2008) using thermogravimetry and differential scanning calorimetry. No boiling point was detected; the test item started to disintegrate above 179 °C.