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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

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Physical & Chemical properties

Boiling point

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boiling point
Type of information:
Adequacy of study:
key study
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification
Internationally accepted method, EPI-Suite, EPA (USA)
Justification for type of information:
See attached the QMRF and QPRF for the QSAR model
other: REACH Guidance on QSARs R.6
Principles of method if other than guideline:
Stein, S.E. and Brown, R.L. 1994. Estimation of normal boiling points from group contributions. J. Chem. Inf. Comput. Sci. 34: 581-7.
Specific details on test material used for the study:
SMILES: N1(C(=O)Nc2ccc(Cc3ccc(NC(=O)N4CC4)cc3)cc2)CC1
Key result
Boiling pt.:
550.74 °C
Atm. press.:
1 atm
Remarks on result:
other: QSAR predicted value

MPBPVP predicted that Poly-U has a boiling point of 550.74ºC

The calculated boiling point is 550.74ºC (EPI-Suite, EPA USA/MPBPVP 1.43).
Executive summary:

The calculated boiling point of the substance Poly-U is 550.74ºC (EPI-Suite, EPA USA/MPBPVP 1.43).

Description of key information

Key study. EPI-Suite, MPBPVP v1.43. The calculated value of the boiling point for the test substance is 550.74ºC.

Key value for chemical safety assessment

Boiling point at 101 325 Pa:
550.74 °C

Additional information

Key study: The boiling point of the test substance was determined by using EPI-Suite, MPBPVP v1.43. The calculated value was 550.74ºC.