Registration Dossier
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EC number: 947-919-1 | CAS number: -
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 30 May - 17 Jul 2017
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- GLP compliance:
- no
- Type of method:
- column elution method
- Key result
- Water solubility:
- < 0.56 µg/L
- Temp.:
- 20 °C
- pH:
- 6.3
Reference
The concentrations of the test item in the different test solutions were calculated automatically using the equation of the calibration curve. The results are listed in the following table:
Flow rate [mL/h] |
Fraction No. |
Volume of combined fractions [mL] |
Internal Standard [µg/L] |
Test Item [µg/L] |
6.25 |
1 (1-2) |
20 |
102.58 |
< 0.56 |
2 (3-4) |
20 |
102.58 |
< 0.56 |
|
3 (5-6) |
20 |
102.58 |
< 0.56 |
|
4 (7-8) |
20 |
102.58 |
< 0.56 |
|
5 (9-10) |
20 |
102.58 |
< 0.56 |
|
6 (11-12) |
20 |
102.58 |
< 0.56 |
|
7 (13-14) |
20 |
102.58 |
< 0.56 |
|
8 (15-16) |
20 |
102.58 |
< 0.56 |
|
3.25 |
1 (1-2) |
20 |
102.58 |
< 0.56 |
2 (3-4) |
20 |
102.58 |
< 0.56 |
|
3 (5-6) |
20 |
102.58 |
< 0.56 |
|
4 (7-8) |
20 |
102.58 |
< 0.56 |
|
5 (9-10) |
20 |
102.58 |
< 0.56 |
|
6(11-12) |
20 |
102.58 |
< 0.56 |
|
7(13-14) |
20 |
102.58 |
< 0.56 |
|
8 (15-16) |
20 |
102.58 |
< 0.56 |
The test item could not be detected in the collected fractions, hence the water solubility of the test item is considered to be below the detection limit of the analytical method (< 0.56 µg/L).
With reference to column 2 of Annex VII to REACH "If the substance appears 'insoluble' in water, a limit test up to the detection limit of the analytical method shall be performed", the water solubility of the test item is reported as < 0.56 µg/L.
The water solubility was determined at 20 °C.
The pH value of the collected aqueous fractions was 6.3.
Description of key information
Water solubility < 0.56 µg/L at 20 °C, pH 6.3 (OECD Guideline 105, column elution method)
Key value for chemical safety assessment
Additional information
The test item could not be detected in the collected fractions, hence the water solubility of the test item is considered to be below the detection limit of the analytical method (< 0.56 µg/L).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
