Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
supporting study
Study period:
not stated
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: MSDS, original study not available

Data source

Reference
Reference Type:
secondary source
Title:
Unnamed

Materials and methods

Principles of method if other than guideline:
no data available
GLP compliance:
not specified
Test type:
other: no data

Test material

Constituent 1
Chemical structure
Reference substance name:
(3R)-4-carbamoyl-3-(4-chlorophenyl)butanoic acid; (3S)-4-carbamoyl-3-(4-chlorophenyl)butanoic acid
EC Number:
700-336-4
Cas Number:
1141-23-7
Molecular formula:
C11H12ClNO3
IUPAC Name:
(3R)-4-carbamoyl-3-(4-chlorophenyl)butanoic acid; (3S)-4-carbamoyl-3-(4-chlorophenyl)butanoic acid
Constituent 2
Reference substance name:
5-amino-3-(4-chlorophenyl)-5-oxopentanoic acid
IUPAC Name:
5-amino-3-(4-chlorophenyl)-5-oxopentanoic acid
Details on test material:
no data available

Test animals

Species:
rat
Strain:
not specified
Sex:
not specified

Administration / exposure

Route of administration:
other: oral
Vehicle:
not specified
Details on oral exposure:
no data available
Doses:
no data available
Control animals:
not specified
Details on study design:
no data available
Statistics:
no data available

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LD50
Effect level:
800 mg/kg bw

Applicant's summary and conclusion

Interpretation of results:
harmful
Remarks:
Migrated information Criteria used for interpretation of results: EU
Executive summary:

Oral rat LD50=800 mg/kg.