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EC number: 947-945-3 | CAS number: -
Based upon the data available on the important physico-chemical properties and results of the acute oral and dermal exposure; it can be concluded that cardanol shall have low bio-accumulation potential.
There is no data available pertaining to the toxico-kinetics of cardanol. Therefore the absorption, distribution, metabolism and excretion (ADME) behavior have been derived based upon the properties of the chemical and results of the acute oral and dermal toxicity testing. It is also important to note that considering the use of cardanol as an industrial chemical, dermal absorption is the only likely route of absorption. However, in the acute toxicity testing by the dermal route, the LD50 was experimentally determined to be > 2000 mg/kg bw indicating no adverse effect by dermal absorption. The bio-concentration factor (BCF) values for the chemical are also < 500, indicating that the potential for bio-accumulation of cardanol is low
Thus, based on all the above considerations, it is concluded that cardanol shall have low bio-accumulation potential.
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