Registration Dossier
Registration Dossier
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EC number: 236-818-1 | CAS number: 13497-18-2
Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Freshwater
- Hazard assessment conclusion:
- no hazard identified
Marine water
- Hazard assessment conclusion:
- no hazard identified
STP
- Hazard assessment conclusion:
- no hazard identified
Sediment (freshwater)
- Hazard assessment conclusion:
- no hazard identified
Sediment (marine water)
- Hazard assessment conclusion:
- no hazard identified
Hazard for air
Air
- Hazard assessment conclusion:
- no hazard identified
Hazard for terrestrial organisms
Soil
- Hazard assessment conclusion:
- no hazard identified
Hazard for predators
Secondary poisoning
- Hazard assessment conclusion:
- no potential for bioaccumulation
Additional information
Conclusion on classification
KEY PARAMETERS FOR CLASSIFICATION
The registered substance 3-(triethoxysilyl)-N-[3-(triethoxysilyl)propyl]-1-propanamine (CAS 13497-18-2) hydrolyses rapidly in contact with water (DT50 = 11.9 h at pH 7 and 20 °C, OECD 111) to 3-(trihydroxysilyl)-N-[3-(hydroxysilyl)propyl]-1-propanamine and ethanol. REACH guidance R.16 states that “for substances where hydrolytic DT50 is less than 12 h, environmental effects are likely to be attributed to the hydrolysis product rather than to the parent itself” (ECHA, 2016). The environmental hazard and risk assessment is therefore based on the silanol hydrolysis product, i.e. 3-(trihydroxysilyl)-N-[3-(hydroxysilyl)propyl]-1-propanamine. The other, alcohol hydrolysis product, ethanol, is not expected to affect the environmental hazard profile of the parent substance (OECD SIDS, 2004). However, since the hydrolysis half-life of the registered compound is close to the cut-off value of 12 hours and for the sake of completeness, the environmental hazard and risk assessment in this dossier also considers the parent compound.
Abiotic degradation - Hydrolysis
DT50 = 11.9 h at pH 7 and 20 °C (OECD 111)
Biodegradation in water
Parent: Not readily biodegradable (62 - 64.5% in 28 d, OECD 301 C and OECD 306)
Silanol HP: Not readily biodegradable (62 - 64.5% in 28 d, OECD 301 C and OECD 306)
Bioaccumulation
log Kow (parent) = 3.1 (20 °C, QSAR)
log Kow (silanol hydrolysis product) = -4.0 (20°C, QSAR)
BCF (silanol hydrolysis product) < 4.2 (RA CAS No. 82985 -35 -1)
Aquatic acute toxicity
Fish
LC50 (96 h) > 200 mg/L (nominal, Scophthalmus maximus, OECD 203)
Aquatic invertebrates
EC50 (48 h) > 151.9 mg/L (meas. init., Acartia tonsa, ISO 14669)
Aquatic algae
ErC50 (72 h) = 125 mg/L (nominal, marine alga Phaeodactylum tricornutum, ISO 10235)
Aquatic chronic toxicity
Aquatic algae
ErC10 (72 h) = 68 mg/L (nominal, marine alga Phaeodactylum tricornutum, ISO 10235)
Classification according to CLP
3-(triethoxysilyl)-N-[3-(triethoxysilyl)propyl]-1-propanamine (CAS 13497-18-2) hydrolyses rapidly under environmental conditions (DT50 = 11.9 h at pH 7 and 20 °C) to form the silanol hydrolysis product 3-(trihydroxysilyl)-N-[3-(hydroxysilyl)propyl]-1-propanamine
and ethanol. The registered compound and its silanol hydrolysis product are not considered to be readily biodegradable, while the alcohol hydrolysis product ethanol is considered to be readily biodegradable (OECD SIDS, 2004). Acute toxicity data are available for all three trophic levels (fish, aquatic invertebrates, algae) on the registered compound. The L(E)C50 effect values are >100 mg/L in all three trophic levels. Due to the rapid hydrolysis of the parent compound and the duration of the acute aquatic toxicity tests (48 to 96 h), the organisms can be expected to be predominantly exposed to the hydrolysis products of the registered compound. Because the alcohol hydrolysis product ethanol is known for its low environmental hazard with effect values well above the herein tested concentrations (OECD SIDS, 2004), ethanol can be disregarded in the overall environmental hazard assessment. Therefore, 3-(triethoxysilyl)-N-[3-(triethoxysilyl)propyl]-1-propanamine (CAS No. 13497-18-2) and its silanol hydrolysis product 3-(trihydroxysilyl)-N-[3-(hydroxysilyl)propyl]-1-propanamine do not need to be classified and labeled according to the consolidated version of Regulation (EC) No 1272/2008 and further amendments (ATPs).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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