Registration Dossier

Environmental fate & pathways

Hydrolysis

Currently viewing:

Administrative data

Link to relevant study record(s)

Reference
Endpoint:
hydrolysis
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 111 (Hydrolysis as a Function of pH)
Qualifier:
according to guideline
Guideline:
EU Method C.7 (Degradation: Abiotic Degradation: Hydrolysis as a Function of pH)
GLP compliance:
no
Remarks:
The hydrolysis rate is too fast and rigorous guideline test is not possible.
Specific details on test material used for the study:
- Supplier: Borica Co., Ltd.
- Lot number: 210524Y
- Expiration date of the lot/batch: 2018-Dec-24
- CAS number: 1071-76-7
Radiolabelling:
no
Analytical monitoring:
yes
Details on sampling:
Initial observations showed rapid degradation in minutes in diluted form.
Only performed at 'natural' pH; it is known that pH does not influence the rate of degradation of these highly unstable substances.
The concentration of test substance in the test sample was determined at time points between 0 & 60 minutes based on quantification of the hydrolysis product. Sampling point: 0, 5, 10, 25, 40, 60 min.
Buffers:
- pH: 7
Conc. 0.01 M
pH 7 Phosphate
Duration:
60 min
pH:
7
Temp.:
30 °C
Number of replicates:
2
Positive controls:
no
Negative controls:
yes
Remarks:
(Blank buffer solutions)
Preliminary study:
The hydrolysis products (transformation products) were identfied.
Transformation products:
yes
No.:
#1
Details on hydrolysis and appearance of transformation product(s):
The solution immediately became cloudy and white precipitation forms when water was added into the Test Substance, indicating the rapid hydrolysis behavior of the Test Substance.
Key result
pH:
7
Temp.:
30 °C
DT50:
<= 5 min
Validity criteria fulfilled:
yes
Conclusions:
The hydroylsis half-life of the test subsatnce was less than 5 minute.
Executive summary:

The recorded degradation products are zirconium dioxide and 1-butanol.  The organic products are known to biodegrade readily.

Description of key information

Test conducted according to OECD guideline 111.

Key value for chemical safety assessment

Half-life for hydrolysis:
5 min
at the temperature of:
30 °C

Additional information

Degrades rapidly when diluted in water, with the visible formation of zirconium oxide as a precipitate within minutes of adding to water.  

Half-life not possible to measure, but considered to be less than 5 minutes.

.