Registration Dossier
Registration Dossier
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EC number: 225-898-3 | CAS number: 5138-18-1
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- (Q)SAR
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification
- Justification for type of information:
- see attached justification.
The most structure similar
Data source
Reference
- Reference Type:
- other: QSAR report
- Title:
- Unnamed
- Year:
- 2 017
- Report date:
- 2017
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- Version / remarks:
- (Q)SAR
- Principles of method if other than guideline:
- Ready Biodegradability model (IRFMN) (version 1.0.9)
QSAR classification model for Ready Biodegradability based on fragments built by SarPy software.
Developed by Politecnico di Milano, Italy and Istituto di Ricerche Farmacologiche Mario Negri, Italy.
LogP model (Meylan/Kowwin) (version 1.1.4)
LogP prediction based on Meylan work (W.M. Meylan, P.H. Howard, "Atom/fragment contribution method
for estimating octanol-water partition coefficients", 1995, J. Pharm. Sci. 84:83-92) and implemented in EPI
Suite software as KowWin. Model developed inside the VEGA platform.
Test material
- Reference substance name:
- Sulphosuccinic acid
- EC Number:
- 225-898-3
- EC Name:
- Sulphosuccinic acid
- Cas Number:
- 5138-18-1
- Molecular formula:
- C4H6O7S
- IUPAC Name:
- sulphosuccinic acid
- Test material form:
- not specified
- Details on test material:
- theoretical substance for (Q)SAR
Constituent 1
Results and discussion
% Degradation
- Key result
- Remarks on result:
- readily biodegradable based on QSAR/QSPR prediction
Applicant's summary and conclusion
- Validity criteria fulfilled:
- not applicable
- Interpretation of results:
- under test conditions no biodegradation observed
- Conclusions:
- Prediction is Readily Biodegradable
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