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Diss Factsheets
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EC number: 272-964-2 | CAS number: 68921-83-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
The key values are based on two guideline studies performed under GLP. The studies examined the acute toxicity in Daphnia magna (invertebrate) and a freshwater algal species. Both studies included analytical support. The reliability of analysis of samples taken from the test solutions during the exposure periods was rather limited due issues with stability of the analytical system and the relatively high limit of detection in case of one of the two peaks used for quantification.
Analysis of the samples taken from the stocks in acetone from the test with Daphnia showed that these solutions had been prepared properly with measured concentrations of ≥80% relative to the target concentrations. In the definitive algal growth inhibition test, concentrations measured in the acetone stock solutions ranged between 98-179% of the nominal concentration level.
The concentrations measured in the test solutions do not reliably represent actual exposure concentrations of the test item due to the limited quality and repeatability of the analytical measurements. Attempts to improve the analytical method and repeating the aquatic tests did not result in more reliable measurements. Based on these observations, it was decided to use the EC50 values based on nominal concentrations as the key values for the hazard assessment of acute aquatic toxicity.
The 48h-EC50 based on nominal concentrations for Daphnia magna exposed to Quaternium-70 was 0.66 mg Q-70/L (95% confidence interval between 0.56 and 0.78 mg Q-70/L).
The EC50 for growth rate inhibition of freshwater algae (72h-ErC50) was 0.43 mg Q-70/L with a 95% confidence interval ranging from 0.23 to 0.86 mg Q-70/L. The 72h-NOEC for growth rate inhibition was 0.010 mg Q-70/L.
Additional information
As both the 48 hr EC50 for crustacea and 72 hr ErC50 for algae ≤ 1 mg/l the classification is Category 1 for acute toxicity with an M-factor of 1.
As the substance is rapidly degradable and the NOEC for algae ≤0.01 mg/l the classification is also Category 1 for chronic toxicity with an M-factor of 1.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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