Registration Dossier

Diss Factsheets

Administrative data

Link to relevant study record(s)

Description of key information

The Henry's Law Constant (HLC) of SOLVENT N1 is calculated to be ca. 21 x E104 Pa·m3/mol.

Basing on such value SOLVENT N1 is anticipated to have rapid volatilization from water.

Key value for chemical safety assessment

Henry's law constant (H) (in Pa m³/mol):
206 559
at the temperature of:
20 °C

Additional information

The Henry's Law Constant (HLC) of SOLVENT N1 is calculated according to the following equation:

Henry's Law Constant (HLC) = (VP x MOLW) / WS

(Reference: Guidance on Information Requirements and Chemical Safety Assessment_ Chapter R.16:

Environmental Exposure Estimation_ Version 3_Equation R.16-4)

where:

VP = Vapour pressure (Pa) of SOLVENT N1 = 30110 Pa (at 20°C)

MOLW = Molecular Weight (g/mol) = ca. 260 g/mol (weighted average for SOLVENT N1 reaction mass)

WS = Water solubility (mg/L) of SOLVENT N1= 37.9 mg/L (at 20°C)

As reported in Guidance on Information Requirements and Chemical Safety Assessment_Chapter R.7a_v.6., substances with HLC values around 100 Pa·m3/mol, will have a rapid volatilization from water.

Basing on the calculated Henry’s Law constant value, volatilization of SOLVENT N1 from water is expected to be very rapid.