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EC number: 207-005-9 | CAS number: 421-50-1
The ability of 1,1,1 -tyrifluoroacetone to generate acute toxic effects on the mobility of Daphnia magna during an exposure period of 48 hours was investigated using an acute immobilisation test according to the OECD guideline No. 202 and under GLP conditions.
A range-finding test allowed to determine that nominal testing concentrations between 10 and 100 mg/L are acceptable for the main test.
In the main test, daphnids were exposed to 9.9, 11, 19, 35 and 61 mg/L (average exposure concentrations based on measured concentrations at the beginning and at the end of the test) for a 48h-exposeure period. The toxic effects of the test substance was determined by measuring the mobility of Daphnia magna.
Under the test conditions, the 48h-EC50 for Daphnia magna exposed to 1,1,1-trifluoroacetone was 46 mg/L based on average exposure concentrations (95% confidence interval between 35 and 61 mg/L).
Harmful to aquatic invertebrate (OECD 202, GLP compliant, Key Rel. 1)
One key study was identified for acute toxicity to aquatic invertebrates in freshwater .
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