Registration Dossier
Registration Dossier
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EC number: 434-820-9 | CAS number: 106461-41-0
Guidance on Safe Use
Administrative data
First-aid measures
If breathed in : move person into fresh air.
If symptoms persist, call a physician.
In case of skin contact : Take off contaminated clothing and shoes immediately
Wash off immediately with plenty of water
If symptoms persist, call a physician.
Wash contaminated clothing before reuse.
In case of eye contact : Rinse immediately with plenty of water, also under the eyelids, for at least 5 minutes.
Remove contact lenses.
If eye irritation persists, consult a specialist.
If swallowed : rinse mouth with water (only if the person is conscious).
Call a physician immediately.
Most important symptoms and effects, both acute and delayed
Symptoms : Sensitisation
Prolonged or repeated exposure may cause target organ effects
Indication of any immediate medical attention and special treatment needed : Treat symptomatically
Fire-fighting measures
Suitable extinguishing media : Water mist
Dry powder
Foam
Carbon dioxide (CO2)
Sand
Aqueous film forming foam (AFFF).
Use extinguishing measures that are appropriate to local circumstances and the surrounding environment.
Unsuitable extinguishing media : Water spray jet
Specific hazards during fire-fighting : Risk of dust explosion.
Hazardous combustion products : Nitrogen oxides (NOx)
Carbon oxides
Special protective equipment for firefighters : In the event of fire, wear self-contained breathing apparatus.
Further information : In the event of fire, cool tanks with water spray
Avoid dust formation.
Accidental release measures
Personal precautions : Avoid dust formation.
Avoid breathing dust.
Evacuate personnel to safe areas.
Keep away from open flames, hot surfaces and sources of ignition.
Environmental precautions : Should not be released into the environment.
Do not flush into surface water or sanitary sewer system.
Methods for cleaning up : Large spills: Sweep up or vacuum with HEPA filter or via wet cleaning into suitable containers for disposal.
Pick up and arrange without creating dust. Keep in properly labelled containers.
Small spills: Moisten a towel, cover the spill, pick up the spill or use HEPA vacuum.
Large spills + Small spills: Keep in suitable, closed containers for disposal. Treat recovered material as described in the section "Disposal considerations".
Handling and storage
Advice on safe handling : Ensure all equipment is electrically grounded before beginning transfer operations.
To avoid thermal decomposition, do not overheat.
Use personal protective equipment as required.
Keep away from heat and sources of ignition.
Avoid inhalation, ingestion and contact with skin and eyes.
Avoid formation of dust and aerosols.
Advice on protection against fire and explosion : Avoid dust formation.
Hygiene measures : Handle in accordance with good industrial hygiene and safety practice.
Dust explosion class : St2
Requirements for storage areas and containers : To maintain product quality, do not store in heat or direct sunlight. Store in original container. Keep containers tightly closed in a cool, well-ventilated place.
Recommended storage tem-perature : 15 - 25 °C
Transport information
Land transport (UN RTDG/ADR/RID)
- UN number:
- UN 3077
Shipping information
- Proper shipping name and description:
- ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S.
(2,4-dihydro-4-(4-(4-(4-hydroxyphenyl)-1-piperazinyl)phenyl)-2-(1-methylpropyl)-3H-1,2,4-triazol-3-one) - Chemical name:
- 2,4-dihydro-4-(4-(4-(4-hydroxyphenyl)-1-piperazinyl)phenyl)-2-(1-methylpropyl)-3H-1,2,4-triazol-3-one
- Language:
- English
- Labels:
- 9
Special provisions / remarks
- Remarks:
- Hazard Identification Number : 90
Tunnel restriction code : (-)
Remarks : Special Provision 375: Environmentally Hazardous Substances/Marine Pollutants, classified under UN 3077 or UN 3082, packaged in single or combination packagings containing a net quantity per single of inner packaging of 5L or less for liquids or having a net mass per single of inner packaging of 5kg or less for solids are not subject to the ADR/RID/ADN/IMDG/IATA DGR provided the packagings meet the general requirements of 4.1.1.1, 4.1.1.2, and 4.1.1.4 to 4.1.1.8., This substance can be shipped under 'de minimi's quantities' provisions if the net quantity per inner package <= 1mL for liquids or <= 1g for solids and the net quantity per outer package does not exceed 100mL for liquids or 100g for solids and provided packaging provisions of ADR/RID/ADN/IMDG §3.5.1.4 are met.
Inland waterway transport (UN RTDG/ADN(R))
- UN number:
- UN 3077
Shipping information
- Proper shipping name and description:
- ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S.
- Chemical name:
- 2,4-dihydro-4-(4-(4-(4-hydroxyphenyl)-1-piperazinyl)phenyl)-2-(1-methylpropyl)-3H-1,2,4-triazol-3-one
- Language:
- English
- Labels:
- 9
Special provisions / remarks
- Remarks:
- Special Provision 375: Environmentally Hazardous Substances/Marine Pollutants, classified under UN 3077 or UN 3082, packaged in single or combination packagings containing a net quantity per single of inner packaging of 5L or less for liquids or having a net mass per single of inner packaging of 5kg or less for solids are not subject to the ADR/RID/ADN/IMDG/IATA DGR provided the packagings meet the general requirements of 4.1.1.1, 4.1.1.2, and 4.1.1.4 to 4.1.1.8., This substance can be shipped under 'de minimi's quantities' provisions if the net quantity per inner package <= 1mL for liquids or <= 1g for solids and the net quantity per outer package does not exceed 100mL for liquids or 100g for solids and provided packaging provisions of ADR/RID/ADN/IMDG §3.5.1.4 are met.
Marine transport (UN RTDG/IMDG)
- UN number:
- UN 3077
Shipping information
- Proper shipping name and description:
- ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S.
(2,4-dihydro-4-(4-(4-(4-hydroxyphenyl)-1-piperazinyl)phenyl)-2-(1-methylpropyl)-3H-1,2,4-triazol-3-one) - Chemical name:
- 2,4-dihydro-4-(4-(4-(4-hydroxyphenyl)-1-piperazinyl)phenyl)-2-(1-methylpropyl)-3H-1,2,4-triazol-3-one
- Labels:
- 9
- Marine pollutant
Remarksopen allclose all
Air transport (UN RTDG/ICAO/IATA)
- UN number:
- UN 3077
Shipping information
- Proper shipping name and description:
- Environmentally hazardous substance, solid, n.o.s.
(2,4-dihydro-4-(4-(4-(4-hydroxyphenyl)-1-piperazinyl)phenyl)-2-(1-methylpropyl)-3H-1,2,4-triazol-3-one) - Chemical name:
- 2,4-dihydro-4-(4-(4-(4-hydroxyphenyl)-1-piperazinyl)phenyl)-2-(1-methylpropyl)-3H-1,2,4-triazol-3-one
- Labels:
- 9
Special provisions / remarks
- Remarks:
- Packing instruction (cargo aircraft) : 956
Packing instruction (LQ) : Y956
Packing instruction (EQ) : E1
Special Provision A197: Environmentally hazardous substances, classified under UN 3077 or UN 3082, when transported in single or combination packagings containing a net quantity per single or inner packaging of 5 L or less for liquids or having a net mass of 5 kg or less for solids, are not subject to any other provisions of the IATA DGR provided the packagings meet the general provisions of IATA DGR 5.0.2.4.1, 5.0.2.6.1.1 and 5.0.2.8., This substance can be shipped under 'de minimi's quantities' provisions if the net quantity per inner package <= 1mL for liquids or <= 1g for solids and the net quantity per outer package does not exceed 100mL for liquids or 100g for solids and provided packaging provisions of IATA DGR §2.6.10 are met.
SpecialProvisionsopen allclose all
Exposure controls / personal protection
Engineering measures : All personal protective equipment should be based on a risk assessment. Consult a Environment Health Safety expert if necessary.
Engineering controls should be used as the primary means to control possible exposures. Use process enclosures, local exhaust ventilation or other engineering controls to keep exposure levels below recommended exposure limits.
Personal protective equipment
Eye protection : Tightly fitting safety goggles
Hand protection material: Nitrile rubber
Remarks: Take note of the information given by the producer concern-ing permeability and break through times, and of special workplace conditions (mechanical strain, duration of contact). Impervious gloves
Skin and body protection: closed work clothing
disposable one-piece overall
Respiratory protection: Engineering controls should always be the primary method of controlling exposures.
If respiratory protective equipment is needed for certain activities, the type as well as the corresponding protection factor will depend upon the risk assessment and air concentrations, hazards, physical and warning properties of substances present.
Use only respiratory protection that conforms to international/ national standards.
Suitable mask with particle filter P3
Protective measures : The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Stability and reactivity
Reactivity : None reasonably foreseeable.
Chemical stability : Stable under normal conditions.
Possibility of hazardous reactions : Risk of dust explosion.
Conditions to avoid : To avoid thermal decomposition, do not overheat.
Heat, flames and sparks.
Materials to avoid : Oxidizing and spontaneously flammable products
Hazardous decomposition products : Nitrogen oxides (NOx), Carbon oxides
Disposal considerations
Product: Must be incinerated in a suitable incineration plant holding a permit delivered by the competent authorities.
In accordance with National, Federal, State and Local regulations.
Contaminated packaging : Empty containers should be taken to an approved waste handling site for recycling or disposal.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
