Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: oral
Type of information:
(Q)SAR
Adequacy of study:
other information
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
results derived from a (Q)SAR model, with limited documentation / justification

Data source

Reference
Reference Type:
other: QSAR-tool
Title:
Danish (Q)SAR Database prediction for CAS 117-78-2
Bibliographic source:
http://qsar.food.dtu.dk

Materials and methods

Test animals

Species:
rat

Results and discussion

Effect levels
Key result
Dose descriptor:
LD50
Effect level:
3 000 mg/kg bw
Remarks on result:
other: reliability Index: 0.71

Any other information on results incl. tables

Reliability index: <0.3 = Not reliableprediction quality; 0.3-0.5 = borderline prediction quality; 0.5-0.75 = moderate prediction quality; >0.75 = high prediction quality.

Applicant's summary and conclusion

Conclusions:
LD50 oral for rat is 3000 mg/kg/bw/d (calculated)