(2S,3S,4R)-3-ethyl-4-hydroxy-2-(methoxycarbonyl)pyrrolidinium 4-methylbenzenesulfonate

Guidance on Safe Use

Accidental release measures

In case of accidental release:

If product is released or spilled. Take proper precautions to minimize exposure by using appropriate personal protective equipment. The area should the adequately ventilated.

Do not raise dust. Surround spill or powder with absorbents and place a damp cloth or towel over the area to minimize entry of powder into the air. Add excess liquid to allow the material to enter into solution. Capture remaining liquid onto spill absorbents. Place spill materials into leak-proof container for disposal in accordance with applicable waste disposal regulations. Decontaminate the area twice with an appropriate solvent.

Transport information

Shipping

SpecialProvisions

Shipping

Remarks

Marine transport (UN RTDG/IMDG)

Shipping

Remarks

Shipping

Remarks

SpecialProvisions

Exposure controls / personal protection

Exposure control/personal protection:

1. Technical protection measures

Exposure/Engineering controls: Selection and use of containment divides and personal protective equipment should be based on a risk assessment of exposure potential. Use local exhaust and/or enclosure at dust-generating points. Emphasis is to be placed on closed material transfer systems and process containment, with limited open handling of powders. High-energy operations such as milling, particle sizing, spraying or fluidizing should be done within an approved emission control or containment system.

2. Organisational protection measures
Environmental Exposure Controls: Avoid release to the environment and operate within closed systems wherever practicable. Air and liquid emissions should be directed to appropriate pollution control devices. In case of spill, do not release to drains. Implement appropriate and effective emergency response procedures to prevent release or spread of contamination and to prevent inadvertent contact by personnel.

3. Hand protection

Wear nitrile or other impervious gloves if skin contact is possible. Double gloves should be considered. When the material is dissolved or suspended in an organic solvent, wear gloves that provide protection against the solvent.

4. Body protection

Wear appropriate gloves, lab coat, or other protective overgarment if skin contact is likely. Base the choice of protection on the job activity, potential for skin contact and solvents and reagents in use.

5. Eye protection

Wear safety glasses with side shields, chemical splash goggles, or full-face shield, if necessary. Base the choice of protection on the job activity and potential for contact with eyes of face. An emergency eye wash station should be available.

6. Respiratory protection

Choice of respiratory protection should be appropriate to the task and used in addition to existing engineering controls unless industrial hygiene data has demonstrated that this is not needed. For routine powder handling, an approved and properly worn and properly fitted air-purifying respirator with HEPA filters should be used to provide ancillary protection based on the known or foreseeable limitations of existing engineering controls. Use a powered, air-purifying respirator (PAPR) or a positive-pressure air-supplied respirator if there is any potential for uncontrolled release, when exposure levels are not known, or in any other circumstances where air purifying respirators may not provide adequate protection. A powered, air-purifying respirator (PAPR) is to be equipped with HEPA filters or combination filters. The assigned protection factor (APF) of the selected PAPR should be at least 1000.

Other protective measures:

Wash hands in the event of contact with this product/mixture, especially before eating, drinking or smoking. Protective equipment is not to be worn outside the work area (e.g. in common areas or out-of-doors). Decontaminate all protective equipment following use.

Disposal considerations

Waste treatment methods: Used product should be disposed of according to local, state, and federal regulations. Do not send down the drain or flush down the toilet. All wastes containing the material should be properly labelled. Dispose of wastes in accordance to prescribed federal, state, and local guidelines, e.g. appropriately permitted chemical waste incinerator. Rinse waters resulting from spill clean-ups should be discharged in an environmentally safe manner, e.g. appropriately permitted municipal or on-site wastewater treatment facility.