Registration Dossier

Administrative data

Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
1.12.2015 - 31.3.2015
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2015
Report Date:
2015

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
EU Method A.6 (Water Solubility)
GLP compliance:
yes (incl. certificate)
Type of method:
column elution method

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
solid
Details on test material:
Expiration: unlisted
Storage condition of test material: at the room temperature in tightly closed container

Results and discussion

Water solubility
Key result
Water solubility:
0.027 mg/L
Conc. based on:
test mat.
Temp.:
20 °C
pH:
ca. 7

Applicant's summary and conclusion

Conclusions:
The determined water solubility of the test substance, 2-(3’,5’-Dichloro-2’-hydroxyphenyl)-4-quinazolinone, was lower than the limit of quantification of used analytical method (LOQ = 0.0094 mg/L).
Test was performed at the temperature of 20°C.