Reaction products of diethylenetriamine and 2,2'-[(1-methylethylidene)bis(4,1-phenyleneoxymethylene)]bisoxirane

Water solubility

Link to relevant study record(s)

Reference

Endpoint:

water solubility

Type of information:

experimental study

Adequacy of study:

key study

Study period:

This study was conducted between 12 December 2016 and 23 June 2017

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

other: The study is considered to be a reliability 1 as it has been conducted according to OECD TG 105 using an adapted flask method and in compliance with GLP.

Qualifier:

according to guideline

Guideline:

OECD Guideline 105 (Water Solubility)

Version / remarks:

27 July 1995

Deviations:

no

Qualifier:

according to guideline

Guideline:

EU Method A.6 (Water Solubility)

Version / remarks:

EC No. 440/2008 of 30 May 2008

Deviations:

no

GLP compliance:

yes

Type of method:

flask method

Specific details on test material used for the study:

Identification: 4,4'-Isopropylidenediphenol, oligomeric reaction products with 1-chloro-2,3-epoxypropane, reaction products with diethylenetriamine
Appearance/Physical state: Yellow/brown extremely viscous liquid
Batch: Ei3041
Purity: 100% UVCB
Expiry date: 01 May 2021
Storage conditions: Room temperature in the dark

The test item was heated to a maximum of 80 °C to enable sampling for testing.

Key result

Water solubility:

> 95 vol%

Conc. based on:

test mat.

Temp.:

20 °C

pH:

ca. 11.4

Preliminary Test

The preliminary estimate of water solubility was greater than 2.6g/L at20.0°C.

Definitive test

The results of the definitive test for the water solubility are shown in the following table:

Concentration (% w/w)	Observation	pH
5.00	Almost colorless, clear, single phase solution, no undissolved test item	11.2
27.7	Clear, slightly viscous, pale yellow, single phase solution, no undissolved test item	11.5
49.6	Clear, viscous, pale yellow, single phase solution, no undissolved test item	11.6
75.6	Clear, extremely, viscous, yellow single phase solution, no undissolved test item/water	n/a
94.8	Clear extremely viscous (non-malleable) yellow, single phase solution, no undissolved test item/water	n/a

Miscibility greater than 95% w/w at 20.0 ± 0.5 ºC. 

Discussion

The standard EC method A6 and OECD method 105 was not applicable to this test item due to the high indeterminable saturation levels produced. It was therefore not possible to prepare samples at five times the saturation level as recommended in the guidelines. No analysis could be performed for the main test due to the high solubility producing unfilterable mixtures. Therefore the water solubility was determined based on visual inspection.

Conclusions:

The miscibility of the test item has been determined to be greater than 95% w/w of solution at 20.0 ± 0.5 ºC.

Executive summary:

The general physico-chemical properties of 4,4'-Isopropylidenediphenol, oligomeric reaction products with 1-chloro-2,3-epoxypropane, reaction products with diethylenetriamine have been determined. 

Water Solubility. Miscible greater than 95% w/w, usingan adapted flask method, designed to be compatible with Method A.6 Water Solubility of Commission Regulation (EC) No 440/2008 of 30 May 2008 and Method 105 of the OECD Guidelines for Testing of Chemicals, 27 July 1995.

Key value for chemical safety assessment

Water solubility:

18 140 000 mg/L

at the temperature of:

20 °C