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Physical & Chemical properties

Water solubility

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Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
From 15 February 2017 to 2018
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Reason / purpose for cross-reference:
reference to other study
Qualifier:
according to guideline
Guideline:
EU Method A.6 (Water Solubility)
Qualifier:
according to guideline
Guideline:
OECD Guideline 105 (Water Solubility)
GLP compliance:
yes (incl. QA statement)
Type of method:
flask method
Key result
Water solubility:
> 5 - < 200 mg/L
Temp.:
20 °C
Remarks on result:
other: Octyl dihydrogen phosphate measured
Remarks:
An accurate water solubility will be indicated when the experimental phase of the study is over.
Water solubility:
< 20 mg/L
Temp.:
20 °C
Remarks on result:
other: Dioctyl hydrogen phosphate measured
Remarks:
An accurate water solubility will be indicated when the experimental phase of the study is over.

The test iem water solubility was defined (in a worst case approach) as the lowest value obtained for one of the two main constituents.

Conclusions:
The water solubility of the two main constituents of the test item was measured. The test item water solubility was defined (in a worst case approach) as the lowest value obtained for one of the two main constituents. Therefore at 20°C, the test item water solubility is 5 mg/l
An accurate water solubility will be indicated when the experimental phase of the study is over.
Executive summary:

The water solubility of the test item was determined according to recognised guidelines and under GLP. No deviation from the guideline was observed in the study.

The water solubility of the two main constituents of the test item was measured. The test iem water solubility was defined (in a worst case approach) as the lowest value obtained for one of the two main constituents. Therefore at 20°C, the test item water solubility is 5 mg/l

An accurate water solubility will be indicated when the experimental phase of the study is over.

Description of key information

The test item water solubility was determined in a key study of Klimisch validity one, performed according to recognised guideline and under GLP.

Key value for chemical safety assessment

Water solubility:
5 mg/L
at the temperature of:
20 °C

Additional information

The key value used for chemical safety assessment corresponds to the lowest value obtained for one of the two main constituents of the test item.

The experimental phase of the study is still ongoing. An accurate water solubility will be indicated when the phase is over.