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EC number: 204-145-2 | CAS number: 116-53-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
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- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- Study initiation date: 2 December 2009 Study completion date: 16 March 2010
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Version / remarks:
- adopted on 27 July 1995
- Deviations:
- no
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Version / remarks:
- Directive 92/69/EEC, Official Journal L 383 A 1992
- Deviations:
- no
- GLP compliance:
- yes
- Type of method:
- flask method
- Key result
- Water solubility:
- 45 g/L
- Conc. based on:
- test mat.
- Loading of aqueous phase:
- 233.3 g/L
- Incubation duration:
- >= 24 - <= 72 h
- Temp.:
- 20 °C
- pH:
- 2.4
- Remarks on result:
- other: Incubation at 30°C for the time given; afterwards equilibration at 20°C for 24 hours before determination of solubility
- Details on results:
- See below!
- Conclusions:
- Interpretation of results (migrated information): very soluble (> 10000 mg/L)
Water Solubility (at 20°C): 45 g/I - Executive summary:
The water solubility of the test item was determined according to OECD guideline no. 105 [adopted on 27 July 1995] and EU test method A.6 [Directive 92/69/EEC, Official Journal L 383 A 1992] with the flask method. Water solubility (at 20°C): 45 g/l at a pH of 2.45.
The test(s) used to generate this report was (were) carried out in compliance with the principles of Good Laboratory Practice (GLP) in accordance with the currently valid German Chemical Substance Act (Chemikaliengesetz – ChemG), the underlying Commission Directive 2004/10/EC of 11 February 2004 and the relevant OECD decision of the council on 26 November 1997 and that the results fully reflect those found in the study.
Reference
Details on measurements:
Sample | Amount of | Added volume | Shaking time | Analysed carbon | Concentration | pH value2) |
1 | 3.505 | 15 | 24 | 27.3 | 46.5 | 2.45 |
2 | 3.505 | 15 | 24 | 27.2 | 46.3 | 2.44 |
3 | 3.509 | 15 | 48 | 26.4 | 44.9 | 2.44 |
4 | 3.504 | 15 | 48 | 26.0 | 44.3 | 2.44 |
5 | 3.506 | 15 | 72 | 26.3 | 44.8 | 2.45 |
6 | 3.508 | 15 | 72 | 26.3 | 44.8 | 2.44 |
1) calculated from the carbon concentration of the sample solutions and the carbon content of the pure test item (58.75 %)
2) The purified water used for the tests had a pH value of 8.41.
Summay results for samples 1 to 6:
Arithmetic mean value: 45.3 g/L
SD: 0.90 g/L
Relative SD: 2.0%
Water solubility [g/L] specific to incubation time interval at 30°C:
24 h: 46.4
48 h: 44.6
72 h: 44.8
The relative standard deviation (repeatability) of the concentrations in all six samples was smaller than 15 % and the three duplicate sets of samples showed no tendency of increasing concentration
values. Thus the test was satisfactory.
Description of key information
Water solublity (OECD 105): 45 g/L at 20°C and a pH of 2.45
Key value for chemical safety assessment
- Water solubility:
- 45 g/L
- at the temperature of:
- 20 °C
Additional information
The water solubility of the test item was determined compliant with GLP according to OECD guideline no. 105 [adopted on 27 July 1995] and EU test method A.6 [Directive 92/69/EEC, Official Journal L 383 A 1992] with the flask method. Water solubility (at 20°C): 45 g/L at a pH of 2.45.
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