Tall oil, compd. with triethanolamine

Toxicity to aquatic algae and cyanobacteria

Link to relevant study record(s)

Reference

Endpoint:

toxicity to aquatic algae and cyanobacteria

Type of information:

experimental study

Adequacy of study:

key study

Study period:

1986

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

test procedure in accordance with national standard methods

Remarks:

Conducted according to a German Industrial Standard DIN 38412 part 9. A US EPA evaluation assigned the reliability criteria as 2A remarking 'Reliable with restrictions; Acceptable, well-documented publication report which meets basic scientific principles'. The study was also considered valid for use in OECD SIDS review for triethanolamine.

Justification for type of information:

Read across justification is attached in section 13.

Qualifier:

according to guideline

Guideline:

other:

Version / remarks:

DIN 38412, Part 9 (German National Guideline - Acute static growth inhibition)

Principles of method if other than guideline:

Further details on the principle of the method not reported.

GLP compliance:

not specified

Specific details on test material used for the study:

CAS Number: 102-71-6
Identity: Triethanolamine
Purity: Not stated

Analytical monitoring:

no

Vehicle:

not specified

Test organisms (species):

Desmodesmus subspicatus (previous name: Scenedesmus subspicatus)

Details on test organisms:

Species identified as Scenedesmus subspicatus

Test type:

static

Water media type:

not specified

Limit test:

no

Total exposure duration:

96 h

Remarks on exposure duration:

72 h measurement also conducted

pH:

Toxicity tests have been carried out at both constant pH and allowing the pH to increase with increasing triethanolamine concentration.

Reference substance (positive control):

not specified

Key result

Duration:

72 h

Dose descriptor:

EC10

Effect conc.:

7.9 mg/L

Nominal / measured:

nominal

Conc. based on:

not specified

Basis for effect:

growth rate

Remarks on result:

other: solutions not neutralised

Key result

Duration:

72 h

Dose descriptor:

EC50

Effect conc.:

216 mg/L

Nominal / measured:

nominal

Conc. based on:

not specified

Basis for effect:

growth rate

Remarks on result:

other: solutions not neutralised

Duration:

72 h

Dose descriptor:

EC10

Effect conc.:

26 mg/L

Nominal / measured:

nominal

Conc. based on:

not specified

Basis for effect:

growth rate

Remarks on result:

other: solutions neutralised

Duration:

72 h

Dose descriptor:

EC50

Effect conc.:

512 mg/L

Nominal / measured:

nominal

Conc. based on:

not specified

Basis for effect:

growth rate

Remarks on result:

other: solutions neutralised

Validity criteria fulfilled:

yes

Conclusions:

The 96-hour acute toxicity of the test substance to Scenedesmus subspicatus has been adequately characterized. The EC50 (growth rate, 72 h) was 216 mg/L for the non-neutralised test and 512 mg/L for the neutralised test. The EC10 (growth rate, 72 h) was 7.9 mg/L for the non-neutralised and 26 mg/L for the neutralised test.

Executive summary:

In a study according to German Industrial Standard DIN 38412 part 9 the 96- hour acute toxicity of the test substance to Scenedesmus subspicatus has been adequately characterized. Full details of the study are not available but the study was considered valid according to a review by the US EPA which assigned the study a reliability criteria 2A, 'Reliable with restrictions; Acceptable, well-documented publication report which meets basic scientific principles'. The study was also considered valid for use in OECD SIDS review for triethanolamine.

The EC50 (growth rate, 72 h) was 216 mg/L for the non-neutralised test and 512 mg/L for the neutralised test. The EC10 (growth rate, 72 h) was 7.9 mg/L for the non-neutralised and 26 mg/L for the neutralised test.

NOTE: Any of data in this dataset are disseminated by the European Union on a right-to-know basis and this is not a publication in the same sense as a book or an article in a journal. The right of ownership in any part of this information is reserved by the data owner(s). The use of this information for any other, e.g. commercial purpose is strictly reserved to the data owners and those persons or legal entities having paid the respective access fee for the intended purpose.

Description of key information

The acute toxicity of the target substance, Tall oil, compound with triethanolamine, to green algae, was assessed by read-across from its components, distilled tall oil & triethanolamine. Based on read-across data, the target substance is not expected to be hazardous to daphnia, with the lowest measured 72-h EC50 (nominal) of 216 mg/L. The read-across justification document covering this and other endpoints is attached to Section 13.

Key value for chemical safety assessment

EC50 for freshwater algae:

216 mg/L

EC10 or NOEC for freshwater algae:

7.9 mg/L