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Physical & Chemical properties

Vapour pressure

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Administrative data

Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Study period:
October 05, 2016 - October 07, 2016
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2017
Report Date:
2017

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to
Guideline:
OECD Guideline 104 (Vapour Pressure Curve)
Deviations:
no
Qualifier:
according to
Guideline:
EU Method A.4 (Vapour Pressure)
Deviations:
no
GLP compliance:
no
Type of method:
effusion method: by loss of weight or by trapping vaporisate

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
solid: particulate/powder

Results and discussion

Vapour pressureopen allclose all
Key result
Test no.:
#1
Temp.:
20 °C
Vapour pressure:
< 0 Pa
Key result
Test no.:
#2
Temp.:
25 °C
Vapour pressure:
< 0 Pa

Any other information on results incl. tables

 Individual results

Vapour pressure balance

The vapour pressure was measured in the temperature range of 70 °C to 120 °C. The derived vapour pressures at the corresponding temperatures are listed in Table 1.

Table1: Measured vapour pressures and corresponding temperatures

Temperature / °C

Vapour pressure / hPa

70

7.8 × 10-6

80

5.9 × 10-6

90

7.1 × 10-6

100

1.2 × 10-5

110

1.3 × 10-5

120

1.0 × 10-5

Since the test did not yield vapour pressures sufficiently high to extrapolate to 20, 25 and 50 °C these values were estimated. According to the Antoine equation, the vapour pressure can be calculated.

For an extrapolation to lower temperatures a conservative assumption of the Antoine constant C is 273.15. This results in a linear dependency of log(p) of the inverse Temperature 1/T (in K). Values for the resulting slope of the Antoine equation (constant B) for similar substances (e.g. see report 20160366.03) have been estimated to be in the range of -2000. Thus, for a conservative estimation of the vapour pressure of the test item at 20, 25 and 50 °C, a value of -2000 for constant B and a value of 273.15 for constant C, respectively, were used.

The last data point of the measurement at 110 °C was used as the starting point for the calculation. The measured vapour pressure at 110 °C was 1.3× 10-5 hPa.

Based on this assumption, the constant A of the Antoine equation was calculated. Subsequently, the vapour pressure at 20, 25 and 50 °C can be calculated with the Antoine equation.

Table2: Calculated vapour pressure at 20, 25 and 50 °C

T / °C

p / hPa

p / Pa

20

< 3.3×10-7

< 3.3×10-5

25

< 4.2×10-7

< 4.2×10-5

50

< 1.4× 10-6

< 1.4× 10-4

This is a conservative estimation of the vapour pressure of the test item for the listed temperatures. In order to further ensure a conservative approach the vapour pressures were rounded up to the next order of magnitude in order to obtain final upper limit values for the vapour pressure.

Table3: Final upper limit values for the vapour pressure at 20, 25 and 50 °C

T / °C

p / hPa

p / Pa

20

< 1×10-6

< 1×10-4

25

< 1×10-6

< 1×10-4

50

< 1× 10-5

< 1× 10-3

Applicant's summary and conclusion

Executive summary:

Based on the measured vapour pressure at 110 °C, the following upper limit vapour pressure values for the test item were calculated:

 

T / °C

p / hPa

p / Pa

20

< 1×10-6

< 1×10-4

25

< 1×10-6

< 1×10-4

50

< 1× 10-5

< 1× 10-3