Methyl valerate

Water solubility

Link to relevant study record(s)

Reference

Endpoint:

water solubility

Type of information:

experimental study

Adequacy of study:

key study

Study period:

2002

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

guideline study without detailed documentation

Qualifier:

according to guideline

Guideline:

OECD Guideline 105 (Water Solubility)

Deviations:

no

GLP compliance:

no

Type of method:

flask method

Key result

Water solubility:

3 500 mg/L

Temp.:

20 °C

pH:

4.1

Remarks on result:

other: standard deviation: 500 mg/L

Details on results:

Because of the expected instability in water (hydrolysis) the solubility was determined at pH 4 (aqueous buffer solution).

Conclusions:

Methyl valerate can be considered as highly soluble with a water solubility of 3500 +/- 500 mg/l measured at 20 °C and pH 4.1.

Executive summary:

The water solubility of methyl valerate in aqueous buffer solution (pH 4.1) obtained after equilibration at 20 °C was determined using the flask method according to the OECD Guideline 105 (Water Solubility). Measurements were made at 20 °C in accordance with the guidance A.6 of the European Community giving a solubility in aqueous buffer solution (pH 4.1) at 20 °C of 3500 mg/L. Therefore methyl valerate can be considered as highly soluble in water.

Description of key information

Methyl valerate can be considered as highly soluble with a water solubility of 3.5 +/- 0.5 g/l measured at 20 °C and pH 4.1.

Key value for chemical safety assessment

Water solubility:

3 500 mg/L

at the temperature of:

20 °C