Registration Dossier
Registration Dossier
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EC number: 200-955-5 | CAS number: 76-37-9
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Study period:
- not reported
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- documentation insufficient for assessment
Data source
Reference
- Reference Type:
- publication
- Title:
- Unnamed
- Year:
- 1 962
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- GLP compliance:
- no
- Test type:
- standard acute method
Test material
- Reference substance name:
- 2,2,3,3-tetrafluoropropan-1-ol
- EC Number:
- 200-955-5
- EC Name:
- 2,2,3,3-tetrafluoropropan-1-ol
- Cas Number:
- 76-37-9
- Molecular formula:
- C3H4F4O
- IUPAC Name:
- 2,2,3,3-tetrafluoropropan-1-ol
- Test material form:
- not specified
Constituent 1
Test animals
- Species:
- rat
- Strain:
- not specified
- Sex:
- not specified
- Details on test animals or test system and environmental conditions:
- no details reported
Administration / exposure
- Route of administration:
- oral: unspecified
- Vehicle:
- not specified
- Details on oral exposure:
- no details reported
- Doses:
- not specified
- No. of animals per sex per dose:
- not specified
- Control animals:
- not specified
- Details on study design:
- no details reported
- Statistics:
- not specified
Results and discussion
Effect levelsopen allclose all
- Sex:
- not specified
- Dose descriptor:
- LDLo
- Effect level:
- 3 400 mg/kg bw
- Key result
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- > 3 400 mg/kg bw
- Remarks on result:
- not measured/tested
- Remarks:
- LD50 > LDlo
- Mortality:
- not reported
- Clinical signs:
- other: Respiratory impairment, gastric irritation, narcosis, incoordination, and prostration
- Gross pathology:
- not reported
Applicant's summary and conclusion
- Interpretation of results:
- GHS criteria not met
- Conclusions:
- The acute oral LD50 in the rat is greater than 3400 mg/kg bw, which was reported as "approximate lethal dose".
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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