Registration Dossier
Registration Dossier
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EC number: 285-413-6 | CAS number: 85098-62-0
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 30 October 2017
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- flask method
- Key result
- Water solubility:
- > 493 g/L
- Conc. based on:
- test mat.
- Temp.:
- 20 °C
- pH:
- 8.36 - 8.42
- Conclusions:
- The water solubility of the test material was determined to be higher than 493 g/L at 20°C.
- Executive summary:
The water solubility of the test material was determined in a GLP study which was conducted in accordance with the standardised guidelines EU Method A.6 amd OECD 105 following the Shake Flask Method.
Under the conditions of the study the water solubility of the test material was determined to be higher than 493 g/L at 20°C.
Reference
Based on the measured concentrations the test mixtures were homogeneous and the whole amount of the added test substance was dissolved.
pH of the samples varied in the range of 8.36 – 8.42.
Table 1: Results of the determinations of the test material concentrations
Nominal conc (mg/mL) |
pH |
Calculated conc (mg/mL) |
Mean (g/L) |
489 |
8.40 |
497 |
495 |
492 |
|||
489 |
8.36 |
502 |
497 |
492 |
|||
491 |
8.42 |
494 |
493 |
492 |
As the measured concentrations correspond to the total dissolution of the test material, and also based on the justification measurement, the water solubility of the substance is considered to be higher than 493 g/L at 20°C.
Description of key information
The water solubility of the test material was determined to be higher than 493 g/L at 20°C.
Key value for chemical safety assessment
Additional information
The water solubility of the test material was determined in a GLP study which was conducted in accordance with the standardised guidelines EU Method A.6 amd OECD 105 following the Shake Flask Method.
Under the conditions of the study the water solubility of the test material was determined to be higher than 493 g/L at 20°C.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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