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Diss Factsheets
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EC number: 234-433-3 | CAS number: 12003-65-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to fish
Administrative data
- Endpoint:
- short-term toxicity to fish
- Type of information:
- read-across based on grouping of substances (category approach)
- Adequacy of study:
- supporting study
- Reliability:
- 3 (not reliable)
- Rationale for reliability incl. deficiencies:
- other: Age, light conditions, analytical method not specified; loading rate and variation of water characteristics not assessable
- Justification for type of information:
- The solubility of aluminium lanthanum trioxide (AlLaO3) in environmental media is expected to be low since dissolution of AlLaO3 in water resulted in La concentrations < 0.01 mg/L and Al concentrations < 0.03 mg/L after 34 days. Solubility in water is considered a worst-case for environmental media due to its low ionic strength and the absence of complexing ions. The ecotoxicological moieties of concern are aluminium and lanthanum ions.
Thus, in the assessment of aquatic toxicity, data available for different aluminium and lanthanum substances are read-across since aluminium and lanthanum ions are the common ecotoxicological moieties of concern.
Cross-reference
- Reason / purpose for cross-reference:
- reference to same study
Data source
Reference
- Reference Type:
- publication
- Title:
- Nutrient inactivation as a lake restoration procedure - laboratory investigations
- Author:
- Peterson, S.A. et al.
- Year:
- 1 974
- Bibliographic source:
- EPA-660/3-74-032
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: Standard Methods for the Examination of Water and Wastewater
- Version / remarks:
- Thirteenth Edition. American Public Health Association.1971.
- Principles of method if other than guideline:
- The effect of aluminium in the form of sodium aluminate (NaAlO2) on the mortality of the chinook salmon (Oncorhynchus tshawytscha) was tested in a static acute toxicity test. Fish were exposed for a total of 216 h (extended from originally 96 h) to a series of 4 test concentrations, whereupon the mortality was assessed daily.
- GLP compliance:
- not specified
- Remarks:
- Not specified in publication
Test material
- Reference substance name:
- Aluminium sodium dioxide
- EC Number:
- 215-100-1
- EC Name:
- Aluminium sodium dioxide
- Cas Number:
- 1302-42-7
- Molecular formula:
- NaAlO2
- IUPAC Name:
- sodium;dioxoalumanuide
- Details on test material:
- Quality: Reagent grade or better
Constituent 1
Sampling and analysis
- Analytical monitoring:
- yes
- Details on sampling:
- Concentrations were measured at test initiation (0 h) and at test termination (96 h).
Test solutions
- Vehicle:
- no
Test organisms
- Test organisms (species):
- Oncorhynchus tschawytscha
- Details on test organisms:
- TEST ORGANISM
- Common name: Chinook salmon
- Source: Local fish hatcheries at Eagle Creek, Fall Creek and Roaring River
- Age at study initiation: not specified
- Length at study initiation: 12-15 cm
- Weight at study initiation: not specified
ACCLIMATION
- Acclimation period: 14 days
- Acclimation conditions (same as test or not): Same as test (Carbon-filtered tap water; 10 °C)
- Type and amount of food during acclimation: Commercial fish food; in amounts such that a minimal residue remained the following day
- Feeding frequency during acclimation: Daily (No feeding 2 days prior to test initiation)
FEEDING DURING TEST
- Yes, not specified.
Study design
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 216 h
- Remarks on exposure duration:
- The exposure duration was extended from originally 96 h to 216 h.
Test conditions
- Hardness:
- 28 mg/L
- Test temperature:
- 10 °C
- pH:
- 7.0 ± 0.2
- Dissolved oxygen:
- 8-9 mg/L
- Nominal and measured concentrations:
- Nominal: 0 (control), 5, 10, 20, 40 mg Al/L
Measured at test initiation: < 0.02 (control), 0.03, 0.07, 0.04, < 0.02 mg Al/L
Measured at test termination: < 0.02 (control), < 0.02, 0.05, < 0.02, < 0.02 mg Al/L - Details on test conditions:
- TEST SYSTEM
- Test vessel: 20 L wide-mouth, soft-glass containers
- Fill volume: 15 L carbon-filtered tap water
- No. of organisms per vessel: 5
- No. of vessels per concentration (replicates): 2 (only 1 at highest concentration); only 9 instead of 10 organisms at 10 mg Al/L
- No. of vessels per control (replicates): 2
- Biomass loading rate: 5 fish/L
OTHER TEST CONDITIONS
- Adjustment of pH: Adjustment to pH 7.0 ± 0.2 with reagent grade sodium hydroxide (NaOH) or hydrochloric acid (HCl)
- Photoperiod: Not specified
EFFECT PARAMETERS MEASURED (with observation intervals if applicable):
- Mortality; daily
TEST CONCENTRATIONS
- Spacing factor for test concentrations: 2 - Reference substance (positive control):
- no
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 96 h
- Dose descriptor:
- NOEC
- Effect conc.:
- 40 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- element
- Basis for effect:
- mortality (fish)
- Duration:
- 216 h
- Dose descriptor:
- NOEC
- Effect conc.:
- 40 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- element
- Basis for effect:
- mortality (fish)
- Details on results:
- No mortality was observed for the control and for all test concentrations after 96 h. Only 1 fish, whose caudal film had been chewed by the others, died in the 40 mg/L concentration at 120 hours.
Any other information on results incl. tables
- Sublethal observations / clinical signs:
Table 1: Dissolved aluminium concentrations, sodium aluminate fish bioassay
Added Aluminium Concentration
Aluminium concentration at 0 hours (mg/L)
Aluminium concentration at 96 hours (mg/L)
0.0 (Control)
< 0.02
< 0.02
5.0
0.03
< 0.02
10.0
0.07
0.05
20.0
0.04
< 0.02
40.0
< 0.02
< 0.02
Applicant's summary and conclusion
- Validity criteria fulfilled:
- no
- Remarks:
- Measured concentrations < 80 % of nominal concentrations; Variation of water characteristics not assessable
- Conclusions:
- In a static acute toxicity test according to the test guideline "Standard Methods for the Examination of Water and Wastewater" (13th edition, APHA, 1971), Chinook salmon (length: 12-15 cm; age not specified) were exposed to aluminium in the form of sodium aluminate in carbon-filtered tap water for a duration of 216 h. No mortality could be observed after 96 h and the extended exposure duration of 216 h for any of the test concentrations. The measured concentration of dissolved aluminium did not increase with increasing concentrations of added sodium aluminate (analytical method not specified).
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