Registration Dossier
Registration Dossier
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EC number: 201-150-1 | CAS number: 78-85-3
Endpoint summary
Administrative data
Description of key information
In a 48-hour acute toxicity study, neonate Daphnia magna were exposed to Methacrolein at nominal concentrations of 0 (control), 0.46, 1.0, 2.2, 4.6 and 10 mg/L under static conditions under light exclusion in accordance with the OECD 202 guideline. The water pH, temperature and dissolved oxygen were within acceptable guideline specifications. Immobilization (mortality) and sublethal effects were observed daily. The 48 hour EC50 values determined in this acute toxicity study were 0.938 mg/L based on the nominal concentration of the test substance (BASF, 2018).
Data are available for the analog substance acrylaldehyde (CAS 107-02-8).
For fish (Pimephales promelas) a LC50 (96 h) of 19.5 µg/L was determined and for invertebrates (Daphnia magna) an EC50 of 0.09 mg/L were measured. Based on the growth rate the EC50 (72 h) for algae (Despodesmus subspicatus) was determined to be 0.061 mg/L.
In the chronic studies NOEC's of 0.0114 mg/L after 60 d for fish (Pimephales promelas), 0.0169 mg/L after 64 d for invertebrates (Daphnia magna) and 0.01 mg/L after 72 h for algae (Desmodesmus subspicatus) were determined.
Additional information
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