Registration Dossier
Registration Dossier
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EC number: 947-167-4 | CAS number: -
Adsorption / desorption
Administrative data
Link to relevant study record(s)
Description of key information
The adsorption coefficient of the test item was determined to be > 4.27 x 10E05 with Log10 Koc > 5.63 (OECD 121 and EU Method C.19).
Key value for chemical safety assessment
Additional information
GUIDELINE
The determination was carried out using the HPLC screening method, designed to be compatible with Method C.19 Adsorption Coefficient of Commission Regulation (EC) No 440/2008 of 30 May 2008 and Method 121 of the OECD Guidelines for Testing of Chemicals, 22 January 2001.
METHODS
The test utilised a High Performance Liquid Chromatograph. A commercially available cyanopropyl reverse phase HPLC column containing lipophilic and polar moieties was used. The dead time was determined by measuring the retention time of formamide (purity quoted by supplier: 99.94%) at 820 mg/L in methanol:water (55:45). Solutions of reference standards were prepared in methanol and test item (0.1018 g) was diluted to 10 mL with tetrahydrofuran to give a concentration of 10.2 g/L
RESULTS
The adsorption coefficient of the test item was determined to be > 4.27 x 10E05 with Log10 Koc > 5.63.
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