Registration Dossier
Registration Dossier
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EC number: 209-269-0 | CAS number: 564-20-5
Partition coefficient
Administrative data
Link to relevant study record(s)
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- September 2021 - January 2022
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
- Version / remarks:
- 13 April 2004
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- HPLC method
- Partition coefficient type:
- octanol-water
- Analytical method:
- high-performance liquid chromatography
- Key result
- Type:
- log Pow
- Partition coefficient:
- 4.5
- Temp.:
- 25 °C
- pH:
- 4
- Key result
- Type:
- log Pow
- Partition coefficient:
- 4.5
- Temp.:
- 25 °C
- pH:
- 7
- Key result
- Type:
- log Pow
- Partition coefficient:
- 4.5
- Temp.:
- 25 °C
- pH:
- 9
- Details on results:
- The measurement of the test item resulted in a clearly distinguishable peak.
The two measurements made under identical conditions and using the same set of reference items fall within a range of ± 0.1 log units. The requirements of OECD guideline 117 concerning the quality criteria were fulfilled. - Conclusions:
- Partition coefficient value of sclareolide measured at pH 4, 7 and 9 amount to 4.5 (log Pow).
- Executive summary:
Partition coefficient value of sclareolide measured at pH 4, 7 and 9 amount to 4.5 (log Pow).
Reference
pH value |
Mean retention time[min] |
Mean Log Pow |
4 |
18.31 |
4.5 |
7 |
18.49 |
4.5 |
Ultra-pure water |
18.52 |
4.5 |
9 |
18.94 |
4.5 |
Description of key information
Key value for chemical safety assessment
- Log Kow (Log Pow):
- 4.5
- at the temperature of:
- 25 °C
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
