Registration Dossier

Physical & Chemical properties

Vapour pressure

Currently viewing:

Administrative data

Link to relevant study record(s)

Reference
Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2011-12-07 - 2013-02-14
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: The GLP study was conducted according to an internationally accepted guideline. All study parameters are given in detail.
Qualifier:
according to
Guideline:
OECD Guideline 104 (Vapour Pressure Curve)
Deviations:
no
GLP compliance:
yes (incl. certificate)
Type of method:
effusion method: by loss of weight or by trapping vaporisate
Temp.:
20 °C
Vapour pressure:
0 Pa
Temp.:
25 °C
Vapour pressure:
0 Pa
Transition / decomposition:
no
Conclusions:
For the test item Ukanol FR 70, the following vapour pressures at 20 °C and at 25 °C were calculated from the regression equation:

Vapour pressure at 20 °C: 6.26 * 10-06 Pa
Vapour pressure at 25 °C: 8.95 * 10-06 Pa
Executive summary:

The vapour pressure of Ukanol FR 70 was determined following EU A.4 by the effusion method (weight loss).

Vapour pressure at nine different temperatures was examined. Experiments 1 - 4 (temperatures 30, 45, 60 and 75 °C) showed no significant weight loss and experiment 7 (temperature 120 °C) was considered as outlier. Therefore, these experiments were not included in the evaluation. Four temperatures were evaluated, but they showed medium to poor reproducibility, giving relative standard deviations of more than 30% (except for experiment 9 at 150 °C which showed a RSD of only 4.6 %). This is considered to be due to the test items purity (90 %). Vapour pressure of mixtures cannot be reasonably determined using a dynamic method (where test item composition changes in the course of the determination); but the static method is not suitable for test items with very low vapour pressures. Therefore, the effusion method was evaluated and the linear regression gave a correlation coefficient r of -0.9971.

Description of key information

The vapour pressure of Ukanol FR 70 was determined following EU A.4 by the effusion method (weight loss).

For the test item Ukanol FR 70, the following vapour pressures at 20 °C and at 25 °C were calculated from the regression equation:

Vapour pressure at 20 °C: 6.26 * 10-06 Pa

Vapour pressure at 25 °C: 8.95 * 10-06 Pa

Key value for chemical safety assessment

Vapour pressure:
0 Pa
at the temperature of:
20 °C

Additional information