Registration Dossier

Physical & Chemical properties

Vapour pressure

Currently viewing:

Administrative data

Link to relevant study record(s)

Reference
Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2013. 8. 26 ~ 2013. 10. 3
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to
Guideline:
OECD Guideline 104 (Vapour Pressure Curve)
Deviations:
no
GLP compliance:
not specified
Type of method:
effusion method: Knudsen cell
Key result
Test no.:
#1
Temp.:
25 °C
Vapour pressure:
0 Pa
Key result
Test no.:
#2
Temp.:
50 °C
Vapour pressure:
0 Pa
Key result
Test no.:
#3
Temp.:
80 °C
Vapour pressure:
0 Pa
Conclusions:
The vapour pressure of GL500 was determined to be 2.62 x 10-6 Pa at 25 °C (298 K), 5.30 x 10-6 Pa at 50 °C (323 K) and 2.83 x 10-5 Pa at 80 °C (353 K), respectively.
Executive summary:

The method is based on the estimation of the mass of test substance flowing out per unit of time of a Knudsen cell in the form of vapour, through a micro-orifice under ultra-vacuum conditions. The mass of

effused vapour can be obtained either by determining the loss of mass of the cell or by condensing the vapour at low temperature and determining the amount of volatilized substance using chromatography.

The vapour pressure is calculated by applying the Hertz-Knudsen relation with correction factors that depend on parameters of the apparatus. The recommended range is 10-10 to 1 Pa.

The evaporation rate was measured under high vacuum at 25 °C (298 K), 50 °C (323 K), 80 °C (353 K) and the weight loss was estimated to be vapour loss. The vapour pressure was calculated by Hertz-

Knudsen equation.

The vapour pressure of GL500 was determined to be 2.62 x 10-6 Pa at 25 °C (298 K), 5.30 x 10-6 Pa at 50 °C (323 K) and 2.83 x 10-5 Pa at 80 °C (353 K), respectively.

Description of key information

The vapour pressure of GL500 was determined to be 2.62 x 10-6 Pa at 25 °C (298 K), 5.30 x 10-6 Pa at 50 °C (323 K) and 2.83 x 10-5 Pa at 80 °C (353 K), respectively.

Key value for chemical safety assessment

Vapour pressure:
0 Pa
at the temperature of:
25 °C

Additional information