Registration Dossier
Registration Dossier
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EC number: 229-713-7 | CAS number: 6674-22-2
Endpoint summary
Administrative data
Description of key information
Substances with an extreme pH (≤ 2 or ≥ 11.5) may represent a potential corrosion hazard for the skin (DBU = pH 12.6). The corrosive potential of DBU was also evaluated using a membrane-barrier test method (Corrositex assay).
The test determined an average crossing time of 20 minutes (calculated on 6 replications) and a substance pH of 14.
Scientifically not necessary study. Substances with an extreme pH (≤ 2 or ≥ 11.5) may produce severe ocular lesions (DBU = pH 12.6).
In addition, corrosive substances for the skin are considered to be capable of causing serious eye damage.
Key value for chemical safety assessment
Skin irritation / corrosion
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (corrosive)
Eye irritation
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (irreversible damage)
Additional information
Bibliographic source:
REACH Registration Dossier, 1,8-diazabicyclo[5.4.0]undec-7-ene
Justification for classification or non-classification
The substance is classified as causes severe skin burns and eye damage. (CLP Regulation - category 1B)
The substance is classified as causes serious eye damage. (CLP Regulation - category 1)
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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