1-(5-propyl-1,3-benzodioxol-2-yl)-1-ethanone

Vapour pressure

Link to relevant study record(s)

Reference

Endpoint:

vapour pressure

Type of information:

experimental study

Adequacy of study:

key study

Study period:

13 -15 January 2014

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Remarks:

The study was conducted according to an internationally recognised method, and under GLP. No deviation was reported. The substance is adequately characterised. Therefore full validation applies.

Qualifier:

according to guideline

Guideline:

OECD Guideline 104 (Vapour Pressure Curve)

Version / remarks:

2006

Deviations:

no

Qualifier:

according to guideline

Guideline:

EU Method A.4 (Vapour Pressure)

Version / remarks:

Regulation (EC) No 440/2008

Deviations:

no

Qualifier:

according to guideline

Guideline:

EPA OPPTS 830.7950 (Vapor Pressure)

Version / remarks:

1996

Principles of method if other than guideline:

Not applicable

GLP compliance:

yes (incl. QA statement)

Remarks:

inspected on January 22 and 23, 2013 / signed on March 22, 2013

Type of method:

effusion method: vapour pressure balance

Specific details on test material used for the study:

STORAGE CONDITIONS OF TEST MATERIAL
Keep in the dark 0-10 °C under nitrogen

Key result

Test no.:

#1

Temp.:

20 °C

Vapour pressure:

0.33 Pa

Test no.:

#2

Temp.:

25 °C

Vapour pressure:

0.59 Pa

Key result

Transition / decomposition:

yes

Transition temp.:

>= 250 °C

Thermal Stability:

In the temperature range of 120 - 130 °C a very small exothermic effect can be observed. At a temperature of 250 °C the test item starts to decompose. The test was terminated at a temperature of 300 °C.

 

Effusion method: Vapour pressure balance

The vapour pressure was measured in the temperature range of 20 to 39 °C.

 

Table 4.6/1: Results of the Effusion method

 

No.	Temperature (°C)	Vapour pressure (Pa)
1	20	0.34
2	21	0.35
3	24	0.51
4	29	0.96
5	33	1.49
6	35	1.87
7	39	2.65

 

The constants of the Antoine equation were derived from the measured data points of the vapour pressure curve:

log10 VP = 14.7698 - 4471.81 / (273.15+T)

The vapour pressure of the test item derived from this regression for the temperatures of 20, 25 and 50 °C were 0.33, 0.59 and 8.54, respectively.

Conclusions:

Low volatility (based on volatility bands criteria for occupational exposure (Chesar / ECETOC TRA), << 500 Pa).

Executive summary:

The vapour pressure of the test substance was measured under GLP according to OECD 104 / EU A4 guideline by effusion (vapour pressure balance) method.

A preliminary thermal stability test by DSC showed decomposition starting from ca 250°C.

A series of seven measurements was recorded between 20 and 39°C, corresponding to 0.34 to 2.65 Pa.

The vapour pressure of the test item was interpolated from the regression to be 0.33 Pa at 20°C, and 0.59 Pa at 25°C.

Description of key information

Low volatility.

Key value for chemical safety assessment

Vapour pressure:

0.33 Pa

at the temperature of:

20 °C

Additional information

A fully reliable experimental study, conducted according to a recognized OECD/EC method and under GLP, is available. It is considered as a key study. The result is retained as key data.