Registration Dossier

Administrative data

First-aid measures

If inhaled:
If breathed in, move person into fresh air.
Artificial respiration and/or oxygen may be necessary.
Take victim immediately to hospital.

In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and water.
Call a physician immediately.

In case of eye contact:
Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes.
Remove contact lenses.
Call a physician immediately.

If swallowed:
If swallowed, rinse mouth with water (only if the person is conscious).
Call a physician immediately.

Fire-fighting measures

Suitable extinguishing media: water mist, dry powder, foam, carbon dioxide, sand, aqueous film forming foam, use extinguishing measures that are appropriate to local circumstances and the surrounding environment.

Unsuitable extinguishing media: water spray jet.

Hazardous combustion products: nitrogen oxides, carbon oxides, fluorine compounds.

Special protective equipment for firefighters: in the event of fire, wear self-contained breathing apparatus. Firefighters must wear fire resistant personal protective equipment.

Accidental release measures

Personal precautions: use personal protective equipment.

Environmental precautions: should not be released into the environment.

Methods for cleaning up:
Large spills: Sweep up or vacuum with HEPA filter or via wet cleaning into suitable containers for disposal. Pick up and arrange without creating dust. Keep in properly labelled containers.
Small spills: Moisten a towel, cover the spill, pick up the spill or use HEPA vacuum.
Large spills + Small spills: Keep in suitable, closed containers for disposal. Treat recovered material as described in the section "Disposal considerations".

Handling and storage

Advice on safe handling:
Ensure all equipment is electrically grounded before beginning transfer operations. To avoid thermal decomposition, do not overheat.
Use personal protective equipment as required.

Advice on protection against fire and explosion:
Avoid dust formation.

Storage temperature:
15 - 25 °C

Transport information

Land transport (ADR/RID)

UN number:
3077
Proper shipping name and description:
ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S.
((+)-[S-(R*,S*)]-6-fluoro-3,4-dihydro-alpha-[[(phenylmethyl)amino]methyl]-2H-1-benzopyran-2-methanol.)
Chemical name:
(+)-[S-(R*,S*)]-6-fluoro-3,4-dihydro-alpha-[[(phenylmethyl)amino]methyl]-2H-1-benzopyran-2-methanol
Language:
English
Class:
9
Classification code:
M7
Packaging group:
III
Labels:
9
Special Provisions:
Special Provision 375: Environmentally Hazardous Substances/Marine Pollutants, classified under UN 3077 or UN 3082, packaged in single or combination packagings containing a net quantity per single of inner packaging of 5L or less for liquids or having a net mass per single of inner packaging of 5kg or less for solids are not subject to the ADR/RID/ADN/IMDG/IATA DGR provided the packagings meet the general requirements of 4.1.1.1, 4.1.1.2, and 4.1.1.4 to 4.1.1.8., This substance can be shipped under 'de minimi's quantities' provisions if the net quantity per inner package <= 1mL for liquids or <= 1g for solids and the net quantity per outer package does not exceed 100mL for liquids or 100g for solids and provided packaging provisions of ADR/RID/ADN/IMDG §3.5.1.4 are met.

Inland waterway transport (ADN(R))

UN number:
3077
Proper shipping name and description:
ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S.
((+)-[S-(R*,S*)]-6-fluoro-3,4-dihydro-alpha-[[(phenylmethyl)amino]methyl]-2H-1-benzopyran-2-methanol.)
Chemical name:
(+)-[S-(R*,S*)]-6-fluoro-3,4-dihydro-alpha-[[(phenylmethyl)amino]methyl]-2H-1-benzopyran-2-methanol
Language:
English
Class:
9
Classification code:
M7
Packaging group:
III
Labels:
9
Remarks
Special Provision 375: Environmentally Hazardous Substances/Marine Pollutants, classified under UN 3077 or UN 3082, packaged in single or combination packagings containing a net quantity per single of inner packaging of 5L or less for liquids or having a net mass per single of inner packaging of 5kg or less for solids are not subject to the ADR/RID/ADN/IMDG/IATA DGR provided the packagings meet the general requirements of 4.1.1.1, 4.1.1.2, and 4.1.1.4 to 4.1.1.8., This substance can be shipped under 'de minimi's quantities' provisions if the net quantity per inner package <= 1mL for liquids or <= 1g for solids and the net quantity per outer package does not exceed 100mL for liquids or 100g for solids and provided packaging provisions of ADR/RID/ADN/IMDG §3.5.1.4 are met.

Marine transport (IMDG)

UN number:
3077
Proper shipping name and description:
ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S.
((-)-[R-(R*,S*)]-6-fluoro-3,4-dihydro-alpha-[[(phenylmethyl)amino]methyl]-2H-1-benzopyran-2-methanol.)
Chemical name:
(-)-[R-(R*,S*)]-6-fluoro-3,4-dihydro-alpha-[[(phenylmethyl)amino]methyl]-2H-1-benzopyran-2-methanol
Class:
9
Packaging group:
III
EmS code:
F-A, S-F
Labels:
9
Marine pollutant
Remarks
2.10.2.7: Environmentally Hazardous Substances/Marine Pollutants, classified under UN 3077 or UN 3082, packaged in single or combination packagings containing a net quantity per single of inner packaging of 5L or less for liquids or having a net mass per single of inner packaging of 5kg or less for solids are not subject to the IMDG provided the packagings meet the general requirements of 4.1.1.1, 4.1.1.2, and 4.1.1.4 to 4.1.1.8., This substance can be shipped under 'de minimi's quantities' provisions if the net quantity per inner package <= 1mL for liquids or <= 1g for solids and the net quantity per outer package does not exceed 100mL for liquids or 100g for solids and provided packaging provisions of ADR/RID/ADN/IMDG §3.5.1.4 are met.

Air transport ICAO/IATA

UN number:
2811
Proper shipping name and description:
Environmentally hazardous substance, solid, n.o.s.
((-)-[R-(R*,S*)]-6-fluoro-3,4-dihydro-alpha-[[(phenylmethyl)amino]methyl]-2H-1-benzopyran-2-methanol.)
Chemical name:
(-)-[R-(R*,S*)]-6-fluoro-3,4-dihydro-alpha-[[(phenylmethyl)amino]methyl]-2H-1-benzopyran-2-methanol
Class:
9
Packaging group:
III
Labels:
9
Remarks
substances, classified under UN 3077 or UN 3082, when transported in single or combination packagings containing a net quantity per single or inner packaging of 5 L or less for liquids or having a net mass of 5 kg or less for solids, are not subject to any other provisions of the IATA DGR provided the packagings meet the general provisions of IATA DGR 5.0.2.4.1, 5.0.2.6.1.1 and 5.0.2.8., This substance can be shipped under 'de minimi's quantities' provisions if the net quantity per inner package <= 1mL for liquids or <= 1g for solids and the net quantity per outer package does not exceed 100mL for liquids or 100g for solids and provided packaging provisions of IATA DGR §2.6.10 are met.
SpecialProvisionsopen allclose all

Exposure controls / personal protection

Personal protective equipment
- Eye protection:face-shield.
- Hand protection: nitrile rubber impervious gloves.
- Skin and body protection: closed work clothing, disposable one-piece overall.
- Respiratory protection: engineering controls should always be the primary method of controlling exposures. If respiratory protective equipment is needed for certain activities, the type as well as the corresponding protection factor will depend upon the risk assessment and air concentrations, hazards, physical and warning properties of substances present. Use only respiratory protection that conforms to international/ national standards. Suitable mask with particle filter P3.

Stability and reactivity

Reactivity:
None reasonably foreseeable.

Chemical stability:
Stable under recommended storage conditions.

Conditions to avoid:
Protect from frost, heat and sunlight.

Materials to avoid:
Oxidizing agents.

Disposal considerations

Waste treatment methods: in accordance with local and national regulations.