Registration Dossier
Registration Dossier
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: - | CAS number: -
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Acute toxicity: via oral route
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed
- Dose descriptor:
- LD50
- Value:
- 1 025 mg/kg bw
- Quality of whole database:
- Study conducted according to internationally accepted testing guidelines.
Acute toxicity: via inhalation route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Acute toxicity: via dermal route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Additional information
The solid substance was assessed according to OECD GD 129 (3T3 NRU). Preliminary value of LD50= 1025 mg/kg is confirmed with comparison of similar substances, suggesting a classification for the test item of our interest.
Justification for classification or non-classification
Adopting the WoE approach based on the result of OECD GD 129 on the test item of our interest ( IC50 about 450 μg/ml i.e. LD50= 1025 mg/kg) and considering the data regarding acute oral toxicity available for similar substances, the substance is classified H302 “Harmful if swallowed”” according to the CLP regulation (EC n.1272/2008).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
