Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 616-894-6 | CAS number: 8006-82-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Biodegradation
Biodegradation in water: screening tests
Biodegradability of Black pepper oil (CAS: 8006-82-4) is predicted using OECD QSAR toolbox version 3.3 with log Kow as the primary descriptor. Test substance undergoes 7.9 % degradation by BOD in 28 days. Thus, based on percentage degradation, the test chemical Black pepper oil (CAS: 8006-82-4) was estimated to be not readily biodegradable in water
Biodegradation in water and sediment: simulation tests
Estimation Programs Interface (EPI Suite, 2017) prediction model was run to predict the half-life in water and sediment for the test compoundBlack pepper oil (CAS: 8006-82-4). If released in to the environment,50.2% of the chemical will partition into water according to the Mackay fugacity model level III and the half-life period of Black pepper oilin water is estimated to be 15 days (360 hrs). The half-life (15 days estimated by EPI suite) indicates that the chemical is persistent in water whereas the half-life period of black pepper oil in sediment is estimated to be 135 days (3240 hrs). Based on this half-life value, it indicates that Black pepper oil is persistent in sediment.
Biodegradation in soil
The half-life period ofBlack pepper oil (CAS: 8006-82-4)in soil was estimated using Level III Fugacity Model by EPI Suite version 4.1 estimation database (EPI suite, 2017). If released into the environment, 47.5 % of the chemical will partition into soil according to the Mackay fugacity model level III. The half-life period of Black pepper oil (CAS: 8006-82-4) in soil is estimated to be 30 days (720 hrs).
Additional information
Biodegradation
Biodegradation in water: screening tests
Following studies include the predicted data and experimental study for the target chemical and structurally similar read acoss to conclude the extent of (Black pepper oil (CAS: 8006-82-4) towards Biodegradability in water is summarized as follows:
Biodegradability of Black pepper oil (CAS: 8006-82-4) is predicted using OECD QSAR toolbox version 3.3 with log Kow as the primary descriptor. Test substance undergoes 7.9 % degradation by BOD in 28 days. Thus, based on percentage degradation, the test chemical Black pepper oil (CAS: 8006-82-4) was estimated to be not readily biodegradable in water.
Similar estimated data for the target chemical suggests that the Estimation Programs Interface Suite (EPI suite, 2017) was run to predict the biodegradation potential of the test compound Black pepper oil (CAS: 8006-82-4)in the presence of mixed populations of environmental microorganisms. The biodegradability of the substance was calculated using seven different models such as Linear Model, Non-Linear Model, Ultimate Biodegradation Timeframe, Primary Biodegradation Timeframe, MITI Linear Model, MITI Non-Linear Model and Anaerobic Model (called as Biowin 1-7, respectively) of the BIOWIN v4.10 software. The results indicate that chemical Black pepper oil (CAS: 8006-82-4)is expected to be not readily biodegradable.
The predicted data for the target chemical is supported by the experimental study of structurally similar read acoss 3a,4,7,7a-tetrahydro-4,7-methanoindene (CAS: 77-73-6) from J-check 2017 suggests that theBiodegradation in water test was carried out for 3a,4,7,7a-tetrahydro-4,7-methanoindene according to the OECD Guideline 301 C (Ready Biodegradability: Modified MITI Test (I)) 3a,4,7,7a-tetrahydro-4,7-methanoindene (CAS: 77-73-6) is not readily biodegradable after 14 days (120h). After 14 days (120h) the % degradation is 0%.
Further it is supported by another structurally similar read across from J-check 2017, also indixates that the Biodegradation in water test was carried out for 5-ethylidene-8,9,10-trinorborn-2-ene according to the OECD Guideline 301 C (Ready Biodegradability: Modified MITI Test (I)) 5-ethylidene-8,9,10-trinorborn-2-ene (CAS: 16219-75-3) is not readily biodegradable after 4 wk (672 h). After 4 wk (672 h) the % degradation is 0%.
Biodegradation in water and sediment: simulation tests
Estimation Programs Interface (EPI Suite, 2017) prediction model was run to predict the half-life in water and sediment for the test compoundBlack pepper oil (CAS: 8006-82-4). If released in to the environment,50.2% of the chemical will partition into water according to the Mackay fugacity model level III and the half-life period of Black pepper oilin water is estimated to be 15 days (360 hrs). The half-life (15 days estimated by EPI suite) indicates that the chemical is persistent in water whereas the half-life period of black pepper oil in sediment is estimated to be 135 days (3240 hrs). Based on this half-life value, it indicates that Black pepper oil is persistent in sediment.
Biodegradation in soil
The half-life period ofBlack pepper oil (CAS: 8006-82-4)in soil was estimated using Level III Fugacity Model by EPI Suite version 4.1 estimation database (EPI suite, 2017). If released into the environment, 47.5 % of the chemical will partition into soil according to the Mackay fugacity model level III. The half-life period ofBlack pepper oil (CAS: 8006-82-4)in soil is estimated to be 30 days (720 hrs).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.