2-(2-chlorophenyl)-1-[2-(2-chlorophenyl)-4,5-diphenyl-2H-imidazol-2-yl]-4,5-diphenyl-1H-imidazole

Particle size distribution (Granulometry)

Administrative data

Endpoint:

particle size distribution (granulometry)

Type of information:

experimental study

Adequacy of study:

key study

Study period:

06 June 2017 to 16 June 2017

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2017

Materials and methods

Test guideline

Test guideline 1

Qualifier:

according to guideline

Guideline:

ISO 13320 (Particle size analysis - Laser diffraction methods)

Test guideline 2

Qualifier:

according to guideline

Guideline:

other: CIPAC MT 187 (CTL SOP No. 417)

GLP compliance:

yes (incl. QA statement)

Type of method:

Laser scattering/diffraction

Type of particle tested:

primary particle

Remarks:

small volume (wet) module (SVM) with kerosene as the dispersant

Type of distribution:

volumetric distribution

Test material

Test material information

Constituent 1

Reference substance name:

2-(2-chlorophenyl)-1-[2-(2-chlorophenyl)-4,5-diphenyl-2H-imidazol-2-yl]-4,5-diphenyl-1H-imidazole

EC Number:

230-555-6

EC Name:

2-(2-chlorophenyl)-1-[2-(2-chlorophenyl)-4,5-diphenyl-2H-imidazol-2-yl]-4,5-diphenyl-1H-imidazole

Cas Number:

7189-82-4

Molecular formula:

C42H28Cl2N4

IUPAC Name:

2,2'-bis(2-chlorophenyl)-4,4',5,5'-tetraphenyl-2'H-1,2'-biimidazole

Test material form:

solid: crystalline

Details on test material:

Appearance: Yellow crystalline powder
Test item storage: At room temperature
Stable under storage conditions until: 01 February 2018 (expiry date)

Specific details on test material used for the study:

density 1.29 g/cm3

Results and discussion

Mass median aerodynamic diameter:

194.631 µm

Geometric standard deviation:

>= 2.784 - <= 2.866

Remarks on result:

other: GSD calculated from d50/d15.78

Particle size

Particle size 1

Key result

Percentile:

D10

Mean:

35.789 µm

St. dev.:

0.533

Particle size 2

Key result

Percentile:

D50

Mean:

171.363 µm

St. dev.:

1.094

Particle size 3

Key result

Percentile:

D90

Mean:

377.026 µm

St. dev.:

5.013

Any other information on results incl. tables

	RUN 1	RUN 2	RUN 3	RUN 4	RUN 5	Average**
Volume weighted mean	191.772	194.590	189.310	193.971	194.387	192.806
Median	171.125	171.700	169.381	172.288	172.378	171.363
Mode	217.800	216.577	216.067	217.320	219.077	217.365
MMAD*	194.361	195.014	192.380	195.682	195.784	194.631
d10-10% of material is <	35.161	36.553	35.291	36.233	35.803	35.798
d50-50% of material is <	171.125	171.700	169.381	172.288	172.378	171.363
d90-90% of material is <	374.684	382.130	368.442	379.111	381.037	377.026

All results are in µm

*Mass median aerodynamic diameter

**Average result is calculated from the entirety of data captured in each run and is not a simple arithmetic mean.

1.83 % by volume of sample was seen to be<10.00 µm.

 

Applicant's summary and conclusion

Conclusions:

The particle size analysis was conducted using the small volume (wet) module (SVM) with kerosene as the dispersant gave an MMAD of 194.631 µm. The volume of sample < 10.00 µm was 1.83 %

Executive summary:

The particle size analysis was conducted using the small volume (wet) module (SVM) with kerosene as the dispersant.

Particle Size Analysis using small volume (wet) module (SVM)	Average (µm)
Volume weighted mean	192.806
Median	171.363
Mode	217.365
MMAD (mass median aerodynamic diameter)	194.631
d10 - 10 % of material is <	35.798
d50 - 50 % of material is <	171.363
d90 - 90 % of material is <	377.026