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Ecotoxicological information

Long-term toxicity to fish

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Link to relevant study record(s)

Reference
Endpoint:
long-term toxicity to fish, other
Type of information:
(Q)SAR
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Justification for type of information:
QSAR prediction
Guideline:
other: REACH Guidance on (Q)SAR
Principles of method if other than guideline:
(Q)SAR
Test organisms (species):
no data
Test type:
other: (Q)SAR
Water media type:
freshwater
Dose descriptor:
other: Chronic Value (ChV)
Effect conc.:
2.73 mg/L

ECOSAR Program (v1.11) Results:

See attachment in above summary: Aquatic toxicity - ECOSAR Program (v1.11) Results

Validity criteria fulfilled:
yes
Remarks:
Aliphatic Amines : Maximum LogKow: 8.0 (Chronic Value)
Conclusions:
Estimated Chronic Value : 2.7 mg/L
Intermediate substance is estimated to be harmful to fish with long lasting effects.

Description of key information

Indicated results are "Chronic values" as obtained from ECOSAR 1.11 run on 2,5-Dichloropentylamine

Key value for chemical safety assessment

EC10, LC10 or NOEC for freshwater fish:
2.73 mg/L

Additional information

NOEC could be estimated to around 1.9 mg/L (ChV/√2) as indicated in Practical Guide 5 - How to use and report (Q)SARs 3.0 (March 2016)

Intermediate substance is estimated to be harmful to fish with long lasting effects.