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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

Administrative data

Endpoint:
toxicity to aquatic algae and cyanobacteria
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2010
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2010
Report date:
2010

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 201 (Alga, Growth Inhibition Test)
GLP compliance:
yes (incl. QA statement)

Test material

Constituent 1
Chemical structure
Reference substance name:
1-(aminomethyl)cyclohexaneacetic acid hydrochloride
EC Number:
262-075-8
EC Name:
1-(aminomethyl)cyclohexaneacetic acid hydrochloride
Cas Number:
60142-95-2
Molecular formula:
C9H17NO2.ClH
IUPAC Name:
2-[1-(aminomethyl)cyclohexyl]acetic acid hydrochloride

Sampling and analysis

Analytical monitoring:
yes

Test solutions

Vehicle:
no

Test organisms

Test organisms (species):
Pseudokirchneriella subcapitata (previous names: Raphidocelis subcapitata, Selenastrum capricornutum)

Study design

Test type:
static
Water media type:
freshwater
Limit test:
yes
Total exposure duration:
72 h

Test conditions

Hardness:
0.24 mmol Ca+Mg/L
Test temperature:
21-24°C, controlled at +/-2°C during study period

Results and discussion

Any other information on results incl. tables

NOEC, LOEC; EC-Value and 95% confidence intervals of (0-72h)

Based on nominal concentration of the test item [mg/L]

   Rate-related inhibition
 NOEC  100
 LOEC  > 100
 ErC10  > 100
 ErC20  > 100
 ErC50  > 100
   Inhibition of yield
 NOEC  < 100
 LOEC  100
 EyC10  < 100
 EyC20  > 100
 EyC50  > 100

Applicant's summary and conclusion

Validity criteria fulfilled:
yes
Conclusions:
Slight inhibition on growth of the freshwater green alga was found after 72h exposure.
The NOEC for inhibition of specific growth rate and yield after 72 h were 100 and < 100 mg/L, respectively.
Inhibition of yield growth was < 20%.