Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Key value for chemical safety assessment

Genetic toxicity in vitro

Description of key information

The test item did induce a mutagenic effect in bacterial test systems either in the presence or in the absence of an exogenous metabolising system. Acid Blue 281 caused cytotoxic effects at 50 µg/plate and above in the absence of metabolic activation (S9 mix) in all strains tested.

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (negative)

Genetic toxicity in vivo

Endpoint conclusion
Endpoint conclusion:
no study available

Additional information

Justification for classification or non-classification

The test item did induce a mutagenic effect in bacterial test systems either in the presence or in the absence of an exogenous metabolising system. The test item does not meet the classification criteria for mutagenicity according to the CLP Regulation.