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Registration Dossier
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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
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EC number: 200-340-1 | CAS number: 57-57-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Administrative data
First-aid measures
Inhalation: Immediately transport to hospital; Remove person to fresh air; If breathing is difficult give oxygen
Skin contact: Rinse immediately with plenty of water; Take off immediately all contaminated clothes; Take medical advice
Eye contact: Rinse immediately with plenty of water for at least 15 min.; Take medical advice
Ingestion: Immediately transport to hospital
Fire-fighting measures
Suitable extinguishing media: Carbon dioxide, dry chemical powder or appropriate foam, water spray.
Special risks: In case of fire poisonous and explosive fumes may arise
Personnel protective equipment: Wear self-contained breathing apparatus and chemical protective clothes.
Accidental release measures
Environmental protection: Hold off from drain system, water and soil.
Personnel protection: Wear self-contained breathing apparatus (Filter A, colour brown) and chemical protective clothes, rubber boots and heavy
rubber gloves
Cleaning: Soak up any spillage using absorbent material and dispose of in UN approved chemically resistant containers
Handling and storage
Handling: Only be handled in closed environments (e.g. Glove-Box); All working and chemical handling areas should have washing facilities and eye wash stations clearly marked; Emergency showers must be located nearby.
Storage: At min -25°C, to prevent polymerisation on storage; Store in an secure area with access only for designated persons with appropriate training; Where possible store in the original container which was supplied; keep all
storage containers securely closed
Transport information
Land transport (UN RTDG/ADR/RID)
- UN number:
- 3382
Shipping information
- Proper shipping name and description:
- TOXIC BY INHALATION LIQUID, N.O.S. (beta-proppiolactone)
- Chemical name:
- beta-propiolactone
- Language:
- English
- Labels:
- 6.1
SpecialProvisionsopen allclose all
Inland waterway transport (UN RTDG/ADN(R))
- UN number:
- 3382
Shipping information
- Proper shipping name and description:
- TOXIC BY INHALATION LIQUID, N.O.S. (beta-proppiolactone)
- Chemical name:
- beta-propiolactone
- Language:
- English
- Labels:
- 6.1
Remarksopen allclose all
Marine transport (UN RTDG/IMDG)
- UN number:
- 3382
Shipping information
- Proper shipping name and description:
- TOXIC BY INHALATION LIQUID, N.O.S. (beta-proppiolactone)
- Chemical name:
- beta-propiolactone
- Labels:
- 6.1
Remarksopen allclose all
Air transport (UN RTDG/ICAO/IATA)
- UN number:
- 3382
Shipping information
- Proper shipping name and description:
- TOXIC BY INHALATION LIQUID, N.O.S. (beta-proppiolactone)
- Chemical name:
- beta-propioalactone
Special provisions / remarks
- Remarks:
- Passenger Aircraft: Not permitted for transport
Cargo Aircraft: Not permitted for transport
SpecialProvisionsopen allclose all
Exposure controls / personal protection
Technical protection: The work space and any chemical handling areas must be equipped with suitable ventilation facilities, This is especially important if elevated temperatures are used because of the increased vapour pressure. Any ventilated or extracted air must be processed and purified before being discharged away to the environment in full accordance with any prevailing national regulations on emission limits.
Respiratory protection: In exceptional cases (e.g. in the instance of accidental spillage) it is necessary to put on respiratory protection; For short duration exposure if a breathing mask is to be worn Gas Filter A (Brown) should be used.
Eye protection: Wearing a full face mask is recommended to prevent damage to the eyes by exposure to vapour or aerosols
Hand protection: Use chemical resistant gloves. The integrity of the glove material and the glove fit should both be checked for suitability before use Body protection: Wear either a well fitting long apron together with chemically protective boots, or a chemical protective suit, before use depending on the quantity to be used and the length of possible exposure time
Stability and reactivity
Stability: Stable at storage conditions -25°C
Substances to be avoided: Strong Bases / Acids and Oxidisers
Hazardous decomposition Products: Toxic fumes of Carbon oxides
More information: Store at –25°C (min) and before opening the storage containers allow to warm up to ambient temperature.
After use fill the container headspace with Argon, close and refreeze immediately
Disposal considerations
Dissolve or mix the material with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber; Consider all federal, state and local environmental regulations
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.