Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: inhalation
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
publication
Title:
SAX'S 11th Edition Dangerous Properties of Industrial Materials Volume 3
Author:
Richard J. Lewis Sr.
Year:
2004
Bibliographic source:
Wiley Interscience

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 403 (Acute Inhalation Toxicity)
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
Propiolactone
EC Number:
200-340-1
EC Name:
Propiolactone
Cas Number:
57-57-8
Molecular formula:
C3H4O2
IUPAC Name:
oxetan-2-one

Test animals

Species:
rat
Strain:
not specified
Sex:
not specified

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LC50
Effect level:
ca. 25 ppm
Based on:
not specified
Exp. duration:
6 h

Applicant's summary and conclusion