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Diss Factsheets
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EC number: 214-490-0 | CAS number: 1135-24-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to fish
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1957
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- All compounds were tested at an initial concentration of 5 ppm. Test were conducted for a 24-hour period at a water temperature of 55 deg. F.
- GLP compliance:
- no
- Analytical monitoring:
- no
- Test organisms (species):
- other: Oncorhynchus mykiss (previous name: Salmo gairdneri) and Lepomis macrochirus
- Details on test organisms:
- Test fishes were of fingerling size, 4 Inches or slightly less in length; every effort was made to keep size variation at a minimum.
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- yes
- Total exposure duration:
- 24 h
- pH:
- 7.5 to 8.2
- Dissolved oxygen:
- 8.6 to 1.7 ppm
- Nominal and measured concentrations:
- one concentration tested = 5 mg/L (5 ppm)
- Details on test conditions:
- Water used in all tests was drawn from a supply pumped directly from Hammond Bay of Lake Huron.
Test fishes were obtained from the stocks of locel state and Federal fish haldleries and were held in large raceways. These specimens were maintained in the best p ssible physical condition until used in the laboratory. - Reference substance (positive control):
- no
- Key result
- Duration:
- 24 h
- Dose descriptor:
- EC0
- Effect conc.:
- 5 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Key result
- Duration:
- 24 h
- Dose descriptor:
- NOEC
- Effect conc.:
- 5 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Validity criteria fulfilled:
- not applicable
- Conclusions:
- With the Ferulic acid no effet were recorded after 24 h of exposure on larvae of the Sea lamprey (Petromyzon marinus) or on rainbow trout or on bluegill sunfish.
- Executive summary:
In this study, several compounds (more than 4000) were tested at an initial concentration of 5 mg/L. Test were conducted for a 24-hour period at a water temperature of 55 deg. F. Observations on the toxic effect of compounds were made on larvae of the sea lamprey (Petromyzon marinus) and also on rainbow trout and bluegill sunfish.
With the Ferulic acid no effect were recorded after 24 h of exposure on larvae of the Sea lamprey (Petromyzon marinus) or on rainbow trout or on bluegill sunfish.
.
Reference
Description of key information
Only one study was found for the fish.
This publication does not cover the essential principal of the OECD guideline test (i.e. only 24 hours exposure, test performed on larvae, concentration etc…) however as there is no other data found on the fish with the ferulic acid this study was used for this trophic level.
Nevertheless in this study, with the Ferulic acid at 5 mg/L no effect were recorded after 24 h of exposure on larvae of the Sea lamprey (Petromyzon marinus) or on rainbow trout or on bluegill sunfish.
As the only concentration tested was 5 mg/L, it cannot be used as key value for this trophic level.
Key value for chemical safety assessment
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.