Registration Dossier
Registration Dossier
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EC number: 202-845-2 | CAS number: 100-37-8
Acute Toxicity: dermal
Administrative data
- Endpoint:
- acute toxicity: dermal
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Secondary quotation with some essential details missing. However, source and authors are acknowledged and thus, the data are considered suitable for assessment of the acute dermal toxicity risk.
Data source
Referenceopen allclose all
- Reference Type:
- publication
- Title:
- Unpublished data from personal communication given through a member of the TLV Committee (November 1964).
- Author:
- Smyth, HF, Jr.
- Year:
- 1 980
- Bibliographic source:
- Cited in: Documentation of the Threshold Limit Values and Biological Exposure Indices, 2-Diethylaminoethanol, pp. 140-141.
- Reference Type:
- other: US EPA TSCA 8(e) submission
- Title:
- Unnamed
- Year:
- 1 942
- Report date:
- 1942
- Reference Type:
- publication
- Title:
- 2-DIETHYLAMINOETHANOL CAS N°:100-37-8, SIDS Initial Assessment Report For SIAM 15
- Author:
- OECD SIDS
- Year:
- 2 004
- Bibliographic source:
- UNEP Publication
Materials and methods
- Principles of method if other than guideline:
- The study was conducted prior to the implementation of current testing guidelines.
- GLP compliance:
- no
- Remarks:
- GLP was not compulsory at the time the study was conducted
- Test type:
- standard acute method
- Limit test:
- no
Test material
- Reference substance name:
- 2-diethylaminoethanol
- EC Number:
- 202-845-2
- EC Name:
- 2-diethylaminoethanol
- Cas Number:
- 100-37-8
- Molecular formula:
- C6H15NO
- IUPAC Name:
- 2-(diethylamino)ethanol
- Details on test material:
- - Name of test material (as cited in study report): 2-diethylaminoethanol
- Analytical purity: not indicated
Constituent 1
Test animals
- Species:
- rabbit
- Strain:
- not specified
- Sex:
- not specified
Administration / exposure
- Type of coverage:
- not specified
- Vehicle:
- not specified
- Duration of exposure:
- no data
- Doses:
- no data
- No. of animals per sex per dose:
- no data
- Control animals:
- not specified
Results and discussion
Effect levels
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- ca. 1 100 mg/kg bw
- Remarks on result:
- other: original value: 1.26 mL/kg bw
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
