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Boiling point

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Reference
Endpoint:
boiling point
Type of information:
experimental study
Adequacy of study:
key study
Study period:
29 November 2017 - 24 January 2018
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Justification for type of information:
The study was conducted according to an internationally recognised method, and under GLP. The test substance is adequately characterised. Therefore full validation applies.
Qualifier:
according to
Guideline:
OECD Guideline 103 (Boiling Point)
Version / remarks:
1995
Deviations:
no
Qualifier:
according to
Guideline:
EU Method A.2 (Boiling Temperature)
Version / remarks:
2008
Deviations:
no
Principles of method if other than guideline:
Not applicable
GLP compliance:
yes (incl. certificate)
Remarks:
Inspected on 13 and 14 October 2014/ signed on 8 april 2015
Type of method:
method according to Siwoloboff
Key result
Boiling pt.:
197.9 °C
Atm. press.:
1 013 Pa
Decomposition:
no

Pre-test:

Observations

Temperatures

Individual small bubbles visible

130 °C

Individual bigger bubbles visible

200 °C

More big bubbles visible, the surface vibrate when bubbles rising up

210 °C

Bubble chain, gas burner switched off

230 °C

Bubble chain broke

215 °C

Less big bubbles visible

210 °C

After cooling down the test item appeared visually unchanged.

Main test:

The following values were recorded:

 

Boiling Point

First determination

197.6 °C (470.8 K)

Second determination

197.3 °C (470.5 K)

In the first determination bubbles immediately occurred after setting the test tube into the aluminium block. A boiling chain was visible at 214.4 °C and the gas burner was switched off. Bubble chain broke at 197.6°C.

In the second determination bubbles were visible at 190.5 °C. A boiling chain was noted again at 214.5 °C and the gas burner was switched off. Bubble chain broke at 197.3°C.

After cooling down the test item appeared visually unchanged.

Results:

The boiling temperatures at standard pressure were calculated following the equation of Sidney-Young (only for small pressure deviations).

 

Boiling point

Pressure in Pa

Corrected Boling point

First determination

197.6 °C (470.8 K)

100335 Pa

197.98 °C (471.13 K)

Second determination

197.3 °C (470.5 K)

100110 Pa

197.77 °C (470.92 K)

Mean

 

 

197.9 °C (471.0 K)

Mean ± standard deviation (after correction following Sydney Young) = 197.9 ± 0.2 °C (471.0 ± 0.2 K) at standard pressure (101.325 kPa).

Conclusions:
The boiling point was performed with the Siwoloboff method.
The boiling point of the test item was determined with 197.9 ± 0.2 °C (corresponding to 471.0 ± 0.2 K). This value is the mean of two independent determinations, corrected to standard pressure (101.325 kPa) using the Sidney-Young equation.
No observations were made which might cause doubts on the validity of the study outcome. Therefore, the result of the study is considered valid.
Executive summary:

The study was performed in order to determine the boiling point of test item according to OECD 103, resp. EU A.2, guideline, using the Siwoloboff method.

The boiling point of the test item was determined with 197.9 ± 0.2 °C (corresponding to 471.0 ± 0.2 K). This value is the mean of two independent determinations, corrected to standard pressure (101.325 kPa) using the Sidney-Young equation.

Description of key information

The boiling point of test item should be stated as: 197.9 ± 0.2 °C (corresponding to 471.0 ± 0.2 K).

Key value for chemical safety assessment

Boiling point at 101 325 Pa:
197.9 °C

Additional information

A fully reliable experimental study, conducted according to OECD 103/ EU A2 guideline is available.

It is considered as a key study, and the result is retained as key data.