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Physical & Chemical properties

Water solubility

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Administrative data

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Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
July 17, 2002 - August 16, 2002
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 105 (Water Solubility)
Version / remarks:
adopted July 27, 1995
Qualifier:
according to guideline
Guideline:
EU Method A.6 (Water Solubility)
Version / remarks:
EEC Publication No. L383, December 1992
GLP compliance:
yes
Type of method:
flask method
Key result
Water solubility:
362.6 g/L
Conc. based on:
test mat.
Incubation duration:
23 h
Temp.:
20 °C
Remarks on result:
completely miscible
Details on results:
The saturation concentration of RED RWa 4565 at room temperature was estimated by a simplified flask method. After mixing a total of about 5 g of test item in 10 ml of water, a dark red solution was obtained. Since the test item was completely dissolved in water, the water solubiliÇ of RED RWa 4565 might therefore be higher as determined in the present study. The determination of the concentration in the above mentioned solution was confirmed by HPLC with respect to a calibration curve.

ln conclusion, the water solubility of the sum of the four main components of RED RWa 4565 at room temperature was determined to be 362.6 g/l.
The water solubility was not corrected for the purity of the test item.

Results obtained for the solubility of RED RWa 4565 in water

 lnitial Weight

of Test ltem (g)

 Water

added (ml)

Dilution factor

 Peak area

 Measured Concentration (mg/l)

 Solubility in water (g/l)

 Mean (g/l)

 4.66

10 

 20 000

 1014609

17.4

 348.0

 

 4.64

10

 20 000

 1099407

18.9

 377.2

 362.6

The tabulated values represent rounded results which were obtained by calculation using the exact raw data.

Conclusions:
The water solubility of the sum of the four main components of RED RWa 4565 at room temperature was determined to be 362.6 g/l.
Executive summary:

The determination of the water solubility of RED RWa 4565 was performed according to the EEC Directive 92/69, 4.6 "Water Solubility'' (1992) and the OECD guideline No. 105, "Water Solubility'' (1995) using the flask shake method.

The saturation concentration of RED RWa 4565 at room temperature was estimated by a simplified flask method. After mixing a total of about 5 g of test item in 10 ml of water, a dark red solution was obtained. Since the test item was completely dissolved in water, the water solubiliÇ of RED RWa 4565 might therefore be higher as determined in the present study. The determination of the concentration in the above mentioned solution was confirmed by HPLC with respect to a calibration curve.

ln conclusion, the water solubility of the sum of the four main components of RED RWa 4565 at room temperature was determined to be 362.6 g/l.

The water solubility was not corrected for the purity of the test item.

Description of key information

The determination of the water solubility of RED RWa 4565 was performed according to the EEC Directive 92/69, 4.6 "Water Solubility'' (1992) and the OECD guideline No. 105, "Water Solubility'' (1995) using the flask shake method.

Key value for chemical safety assessment

Water solubility:
362.6 g/L
at the temperature of:
20 °C

Additional information