Registration Dossier
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EC number: 233-566-4 | CAS number: 10236-47-2
Vapour pressure
Administrative data
Link to relevant study record(s)
- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- July 26th, 2016.
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 104 (Vapour Pressure Curve)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.4 (Vapour Pressure)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- effusion method: Knudsen cell
- Key result
- Test no.:
- #1
- Temp.:
- 20 °C
- Vapour pressure:
- 0 Pa
- Key result
- Test no.:
- #2
- Temp.:
- 25 °C
- Vapour pressure:
- 0 Pa
- Conclusions:
- The vapour pressure of the test item is 2.25E-11 Pa at 20ºC and 7.24E-11 Pa at 25ºC.
- Executive summary:
The study of the vapour pressure using effusion method was performed in accordance with the method EU A4 - Knudsen cell (GLP study). The vapour pressure of the test item was found to be 2.25E-11 Pa at 20ºC and 7.24E-11 Pa at 25ºC.
Reference
The vapour pressure of the test item at 20ºC and 25ºC was calculated on the basis of equation log (p) = f (1/t) = a-b/(t+273.15) where: p – vapour pressure in Pa, t – temperature in ºC, obtained for four measurement points: 148.1ºC, 154.2ºC, 158.1ºC and 162.7ºC. The determined vapour pressure is:
| Test sample | Vapour pressure at 20ºC [Pa] |
Vapour pressure at 25ºC [Pa] |
| Naringin | 2.25·10-11 | 7.24·10-11 |
Description of key information
Key study. Method according to EU A.4, GLP study. The vapour pressure of the test item is 2.25E-11 Pa at 20ºC and 7.24E-11 Pa at 25ºC.
Key value for chemical safety assessment
- Vapour pressure:
- 2.25 Pa
- at the temperature of:
- 20 °C
Additional information
The study of the vapour pressure using effusion method was performed in accordance with the method EU A4 - Knudsen cell (GLP study).The vapour pressure of the test item was found to be 2.25E-11 Pa at 20ºC and 7.24E-11 Pa at 25ºC.
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