3,10-diamino-6,13-dichloro-2-((6-(((4-(1,1-dimethylethyl)phenyl)sulfonyl)amino)-2-naphthalenyl)sulfonyl)-4,11-triphenodioxazinedisulfonic acid, lithium potassium sodium salt

Melting point / freezing point

Link to relevant study record(s)

Reference

Endpoint:

melting point/freezing point

Type of information:

experimental study

Adequacy of study:

key study

Study period:

August 20, 2001 to December 20, 2001

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 102 (Melting point / Melting Range)

Version / remarks:

adopted July 27, 1995

Qualifier:

according to guideline

Guideline:

EU Method A.1 (Melting / Freezing Temperature)

Version / remarks:

EEC Publication No. L383, December 1992

GLP compliance:

yes

Type of method:

differential scanning calorimetry

Key result

Melting / freezing pt.:

> 400 °C

Remarks on result:

not determinable

In the a preliminar test, the quantities of heat absorbed or released off were measured and recorded at heating rate of 20 K/min from 25 °C to 400°C.

Before and after the test, the weight and the appearance of the sample were determined.

A not well defined endothermic heat effect was observed between 50°C and 150 °C. An exothermic heat effect starts at about 250 °C. After the experiment, the sample had lost 13.8 % of its mass and the sample was black and powdery, which indicates that no melting occurred.

In order to confirm the result of the preliminary test a further DSC-run was recorded as main test between 25°C and 400°C with a heating rate of 10 K/min. In this run, no relevant endothermic heat effect was observed. During this run, the sample lost 9.7 % of its mass. After the measurement the sample was still a powder and colored black.

In conclusion, BLUE GS 5664.80 does not melt under the conditions of the test, meaning that melting point is >400°C.

Conclusions:

BLUE GS 5664.80 does not melt under the conditions of the test (between 25 and 400°C), meaning that melting point is >400°C.

Executive summary:

The melting point of BLUE GS 5664.80 has been determined in the current study performed following OECD TG 102 according to GLP. The selected method is Differential Scanning Calorimeter (DSC).

In a preliminar test, the quantities of heat absorbed or released off were measured and recorded at heating rate of 20 K/min from 25 °C to 400°C.

Before and after the test, the weight and the appearance of the sample were determined.

A not well defined endothermic heat effect was observed between 50°C and 150 °C. An exothermic heat effect starts at about 250 °C. After the experiment, the sample had lost 13.8 % of its mass and the sample was black and powdery, which indicates that no melting occurred.

In order to confirm the result of the preliminary test a further DSC-run was recorded as main test between 25°C and 400°C with a heating rate of 10 K/min. In this run, no relevant endothermic heat effect was observed. During this run, the sample lost 9.7 % of its mass. After the measurement the sample was still a powder and colored black.

In conclusion, BLUE GS 5664.80 does not melt under the conditions of the test, meaning that melting point is >400°C.

Description of key information

BLUE GS 5664.80 does not melt under the conditions of the test performed according to the EEC Directive 92/69, A.1 "Melting/Freezing temperature", December 1992 and to the OECD Guideline No. 102: " Melting point I melting range", adopted July 27, 1995